Exposure to an inhomogeneous static magnetic field increases thermal pain threshold in healthy human volunteers
Exposure to an inhomogeneous static magnetic field increases thermal pain threshold in healthy human volunteers
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DOI：
10.1002/bem.20622
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发表时间：
2011-02
影响因子：
1.9
通讯作者：
Z. Kovacs-Balint;Á. Csathó;J. László;Péter Juhász;I. Hernádi
中科院分区：
文献类型：
--
作者：
Z. Kovacs-Balint;Á. Csathó;J. László;Péter Juhász;I. Hernádi
本实验观察了15名健康青年志愿者单次暴露30 min非均匀静磁场对热痛阈的影响。SMF的最大峰间振幅为330 mT，最大梯度为13.2 T/m。在两个实验阶段（SMF或SHAM）中的任何一个中，在SMF或SHAM暴露下对除拇指外的优势手的所有指尖进行了4个区块的12个TPT试验。在0、15和30 min暴露时间以及暴露后30 min记录TPT和视觉模拟量表（VAS）数据。SMF治疗导致整个暴露持续时间内TPT统计学显著性增加，并减少块内热习惯，使疼痛感知保持不变。这些结果表明，SMF诱导的外周神经元或循环机制可能通过将疼痛纤维适应电位设定为更高水平而参与观察到的TPT增加。Bioelectromagnetics 32：131-139，2011.© 2010 Wiley利斯公司
In the present experiment, the effect of a single 30 min inhomogeneous static magnetic field (SMF) exposure on thermal pain threshold (TPT) was examined in 15 young healthy human volunteers. The SMF had a maximum peak‐to‐peak amplitude of 330 mT with a maximum gradient of 13.2 T/m. In either of two experimental sessions (SMF or SHAM), four blocks of 12 TPT trials were carried out under SMF or SHAM exposure on all fingertips of the dominant hand, excluding the thumb. TPT and visual analog scale (VAS) data were recorded at 0, 15, and 30 min exposure time, and 30 min following exposure. SMF treatment resulted in a statistically significant increase in TPT during the entire exposure duration and diminished within‐block thermal habituation, leaving pain perception unchanged. These results indicate that SMF‐induced peripheral neuronal or circulatory mechanisms may be involved in the observed TPT increase by setting the pain fibre adaptation potential to higher levels. Bioelectromagnetics 32:131–139, 2011. © 2010 Wiley‐Liss, Inc.