An evaluation of two self-report screening measures for mood in an out-patient chronic heart failure population
An evaluation of two self-report screening measures for mood in an out-patient chronic heart failure population
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DOI：
10.1002/gps.1807
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发表时间：
2007-11-01
影响因子：
4
通讯作者：
Cleland, J. G. F.
中科院分区：
文献类型：
--
作者：
Haworth, J. E.;Moniz-Cook, E.;Cleland, J. G. F.
目的探讨医院焦虑抑郁量表（HADS）和老年抑郁量表（GDS-15）在社区慢性心力衰竭（CHF）门诊患者中的效标效度。将GDS-15和HADS与来自DSM-IV（SCID-I）的结构化临床访谈的诊断进行比较，使用受试者操作特征（ROC）分析和阳性和阴性预测值、各种截止点的敏感性和特异性。GDS-15的ROC曲线下面积为0.883，截止值为5时，灵敏度为0.818，特异性为0.833。HADS抑郁（D）和焦虑（A）的ROC曲线下面积分别为0.889和0.941。在截止值为7时，HADS-A的灵敏度为0.938，特异性为0.847。以4为界值，HADS-D的敏感性为0.864，特异性为0.788。结论GDS-15和HADS是老年CHF患者抑郁的有效筛查工具。然而，使用HADS需要降低临界点，以确保在该人群中不遗漏心境障碍患者。版权所有（c）2007约翰威利父子有限公司。
Objective To examine the criterion validity of the Hospital Anxiety and Depression Scale (HADS) and the Geriatric Depression Scale 15-item (GDS-15) in a community sample of Chronic Heart Failure (CHF) out-patients,Methods Eighty-eight of 203 older adults with confirmed CHF responded to a postal survey and participated in a face-to-face interview. The GDS-15 and HADS were compared to diagnoses from the Structured Clinical Interview for DSM-IV (SCID-I), using a receiver operating characteristic (ROC) analysis and positive and negative predictive values, sensitivity and specificity for various cut-off points,Results For all depressive disorders, the area under the ROC curve for the GDS-15 was 0.883 and a cut-off of 5 gave a sensitivity of 0.818 and a specificity of 0.833. The area under the ROC curve for the HADS Depression (D) and Anxiety (A) were 0.889 and 0.941 respectively. At a cut-off of 7, the HADS-A gave a sensitivity of 0.938 and a specificity of 0.847. At a cut-off of 4, the HADS-D gave a sensitivity of 0.864 and a specificity of 0.788.Conclusions The GDS-15 and HADS are valid screening tools for detecting depression in aged CHF out-patients. However, use of the HADS requires reduced cut-points to ensure that patients with mood disorder are not missed in this population. Copyright (c) 2007 John Wiley & Sons, Ltd.