Transient hypoparathyroidism following thyroidectomy: A prospective study and multivariate analysis of 604 consecutive patients
Transient hypoparathyroidism following thyroidectomy: A prospective study and multivariate analysis of 604 consecutive patients
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DOI：
10.1016/j.otohns.2007.03.001
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发表时间：
2007-10-01
影响因子：
3.4
通讯作者：
Ceroni, Alberto Rinaldi
中科院分区：
文献类型：
--
作者：
Cavicchi, Ottavio;Piccin, Ottavio;Ceroni, Alberto Rinaldi
目的：本研究的目的是确定一组接受甲状腺手术的患者术后一过性甲状旁腺功能减退的危险因素。研究设计：对604例接受甲状腺手术的患者进行前瞻性研究。性别，最终诊断，切除范围，病理生物学，胸内受累，复发性多结节性甲状腺肿手术，手术标本中甲状旁腺的存在和数量作为术后短暂性甲状旁腺功能减退的危险因素进行分析。结果：在Logistic回归分析中，只有手术范围是一过性甲状旁腺功能减退的独立变量（P = 0.001）。结论：手术至中央和/或或侧颈淋巴结是导致短暂性甲状旁腺功能减退的高发生率的原因，这是由于计划外的甲状旁腺切除术或甲状旁腺切除术的高概率。断流术(c)2007年美国耳鼻咽喉头颈外科学会基金会。All rights reserved.
OBJECTIVE: The purpose of this study was to identify the risk factors for postoperative transient hypoparathyroidism in a group of patients undergoing thyroid surgery.STUDY DESIGN: A prospective study was conducted on 604 patients undergoing thyroid surgery.SUBJECTS AND METHODS: Gender, final diagnosis, extent of resection, biology of pathology, intrathoracic involvement, surgery for recurrent multinodular goiter, and presence and number of parathyroid glands in a surgical specimen were analyzed as risk factors for postoperative transient hypoparathyroidism. The chi-square test and a logistic regression analysis were applied.RESULTS: On logistic regression analysis, only the extent of surgery constituted an independent variable for transient hypoparathyroidism (P = 0.001).CONCLUSION: The extent of surgery to central and/or lateral neck lymph nodes is responsible for a high rate of transient hypoparathyroidism owing to a high probability of unplanned parathyroidectomy or parathyroid gland devascularization. (c) 2007 American Academy of Otolaryngology-Head and Neck Surgery Foundation. All rights reserved.