Measurement of the 3D arterial wall strain tensor using intravascular B-mode ultrasound images: a feasibility study.
Measurement of the 3D arterial wall strain tensor using intravascular B-mode ultrasound images: a feasibility study.
复制标题
使用血管内 B 型超声图像测量 3D 动脉壁应变张量：可行性研究。
DOI：
10.1088/0031-9155/55/21/003
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发表时间：
2010
影响因子：
3.5
通讯作者：
Friedman,MortonH
中科院分区：
文献类型：
--
作者：
Liang,Yun;Zhu,Hui;Friedman,MortonH
血管内超声（IVUS）弹性成像是研究动脉粥样硬化斑块成分和评估斑块易损性的一种有前途的工具。当前的IVUS弹性成像技术可以使用各种运动跟踪算法测量血管壁的1D或2D应变。由于生物软组织倾向于在3D中不均匀地变形，因此完整的3D应变张量的测量对于动脉壁力学的更严格分析是期望的。在本文中，我们扩展了我们以前开发的方法，二维动脉壁应变测量的基础上非刚性图像配准到三维应变测量。新技术配准了在不同水平的管腔压力和纵向应力下从同一血管段采集的两个图像体积。从图像配准获得的3D位移场用于计算局部3D应变张量。从三维应变张量，径向，周向和纵向应变分布可以获得和显示。使用健康猪颈动脉的IVUS图像对应变张量测量方法进行验证和评价，所述健康猪颈动脉经受管腔压力增加和纵向拉伸。测试了该算法克服系统噪声的能力，以及在不同纵向帧分辨率下结果的一致性。
Intravascular ultrasound (IVUS) elastography is a promising tool for studying atherosclerotic plaque composition and assessing plaque vulnerability. Current IVUS elastography techniques can measure the 1D or 2D strain of the vessel wall using various motion tracking algorithms. Since biological soft tissue tends to deform non-uniformly in 3D, measurement of the complete 3D strain tensor is desirable for more rigorous analysis of arterial wall mechanics. In this paper, we extend our previously developed method of 2D arterial wall strain measurement based on non-rigid image registration into 3D strain measurement. The new technique registers two image volumes acquired from the same vessel segment under different levels of luminal pressure and longitudinal stress. The 3D displacement field obtained from the image registration is used to calculate the local 3D strain tensor. From the 3D strain tensor, radial, circumferential and longitudinal strain distributions can be obtained and displayed. This strain tensor measurement method is validated and evaluated using IVUS images of healthy porcine carotid arteries subjected to a luminal pressure increase and longitudinal stretch. The ability of the algorithm to overcome systematic noise was tested, as well as the consistency of the results under different longitudinal frame resolutions.