Responses of the hippocampus to stimulation of the olfactory bulb and of various afferent nerves in five mammals.
Responses of the hippocampus to stimulation of the olfactory bulb and of various afferent nerves in five mammals.
复制标题
五种哺乳动物的海马体对嗅球和各种传入神经刺激的反应。
DOI：
10.1016/0014-4886(60)90031-5
复制
发表时间：
1960
影响因子：
5.3
通讯作者：
B. Cragg
中科院分区：
文献类型：
--
作者：
B. Cragg
研究发现，嗅觉和其他传入冲动到达海马体的比例在所研究的物种之间是不同的。在大鼠同侧嗅球单次电击时，在阿蒙氏角细胞外记录到一个大的神经元动作电位。这种动作电位总是通过刺激的快速重复而增强。在豚鼠中，对单一嗅觉刺激只有很小的动作电位，但快速重复刺激总是出现大的反应。在兔身上，单一的嗅觉刺激引起了自发活动时难以辨别的反应，但在快速重复刺激后，大的神经元动作电位总是出现。在这三种动物中，对其他各种传入神经的刺激，在阿蒙氏角没有记录到任何反应。在猫中，对单一嗅觉刺激的反应通常是小的动作电位，在低重复频率时，许多海马区对嗅觉刺激和对其他传入神经的刺激也能看到明确的反应。猫的反应只是偶尔会被刺激的快速重复所增强。在猴子身上，阿蒙角的一小部分被发现对缓慢重复的嗅觉刺激有反应，对单一电击只有明显的反应。这种反应从未被快速重复刺激所增强，在该区域，刺激其他传入神经也不能引起反应。在兔身上发现了从梨状皮质到海马体前腹侧下弯部分的多突触通路的证据。
The proportion of olfactory and other afferent impulses reaching the hippocampus was found to vary between the species examined. In the rat, a large neuronal action potential was recorded extracellularly in Ammon's horn when single electric shocks were applied to the ipsilateral olfactory bulb. This action potential was invariably augmented by rapid repetition of the stimulus. In the guinea pig, only a small action potential was seen in response to single olfactory stimuli, but a large response always appeared with fast repetitive stimulation. In the rabbit, single olfactory stimuli evoked responses that were hardly discernible in the presence of spontaneous activity, but large neuronal action potentials invariably appeared after fast repetitive stimulation. In these three species, no response was recorded in Ammon's horn to stimulation of various other afferent nerves. In the cat, a small action potential was often seen in response to single olfactory stimuli, and at low rates of repetition, definite responses were seen at many hippocampal placements with olfactory stimuli and often with stimuli applied to other afferent nerves as well. The responses in the cat were only occasionally augmented by rapid repetition of the stimulus. In the monkey, a small part of Ammon's horn was found to respond to slowly repeated olfactory stimuli and to give just discernible responses to single shocks. The responses were never augmented by fast repetitive stimulation, and in this region, were not evoked by stimulation of other afferent nerves. Evidence of a multisynaptic pathway from the prepiriform cortex to the anteroventral recurved part of the hippocampus has been found in the rabbit.