Small cell lung cancer.

Small cell lung cancer.
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DOI:
10.6004/jnccn.2013.0011
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发表时间:
2013-01-01
期刊:
Journal of the National Comprehensive Cancer Network : JNCCN
影响因子:
--
通讯作者:
National Comprehensive Cancer Network
National Comprehensive Cancer Network
中科院分区:
其他
文献类型:
--
作者:
Kalemkerian GP;Akerley W;Bogner P;Borghaei H;Chow LQ;Downey RJ;Gandhi L;Ganti AK;Govindan R;Grecula JC;Hayman J;Heist RS;Horn L;Jahan T;Koczywas M;Loo BW Jr;Merritt RE;Moran CA;Niell HB;O'Malley J;Patel JD;Ready N;Rudin CM;Williams CC Jr;Gregory K;Hughes M;National Comprehensive Cancer Network

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神经内分泌肿瘤约占肺癌的20%;大多数(约15%)是小细胞肺癌(SCLC)。这些NCCN肿瘤学SCLC临床实践指南关注广泛期SCLC,因为它比局限期疾病更常见。SCLC对初始治疗高度敏感;然而,大多数患者最终死于疾病复发。在广泛期疾病患者中,单独化疗可以缓解症状并延长大多数患者的生存期;然而,长期生存是罕见的。大多数SCLC病例可归因于吸烟;因此,应大力提倡戒烟。
Neuroendocrine tumors account for approximately 20% of lung cancers; most (≈15%) are small cell lung cancer (SCLC). These NCCN Clinical Practice Guidelines in Oncology for SCLC focus on extensive-stage SCLC because it occurs more frequently than limited-stage disease. SCLC is highly sensitive to initial therapy; however, most patients eventually die of recurrent disease. In patients with extensive-stage disease, chemotherapy alone can palliate symptoms and prolong survival in most patients; however, long-term survival is rare. Most cases of SCLC are attributable to cigarette smoking; therefore, smoking cessation should be strongly promoted.
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