Author response: Low-density lipoprotein cholesterol and risk of intracerebral hemorrhage: A prospective study

Author response: Low-density lipoprotein cholesterol and risk of intracerebral hemorrhage: A prospective study
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作者回应:低密度脂蛋白胆固醇与脑出血的风险:一项前瞻性研究

DOI:
10.1212/wnl.0000000000009808
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发表时间:
2020
期刊:
影响因子:
9.9
通讯作者:
Xiang Gao
Xiang Gao
中科院分区:
医学1区
文献类型:
--
作者:
Chaoran Ma;Shouling Wu;Xiang Gao

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我们赞赏Sampietro等人的评论。在本研究中,我们没有收集有关他汀类药物使用的具体信息。因此,我们不能检验他汀类药物的使用是否与脑出血(ICH)风险改变有关。有必要进行进一步研究,以了解降脂药物使用与脑出血风险之间的关系。我们同意您的观点,即“在降低心血管风险、避免出血风险和减轻与降脂治疗相关的副作用之间取得最佳平衡是很重要的。”
We appreciate the comment by Sampietro et al. on our article.1 We did not collect specific information on statin use in the current study. We, thus, cannot examine whether statin use was associated with altered risk of intracerebral hemorrhage (ICH). Further studies are warranted to understand a relationship between lipid-lowering medication use and risk of ICH. We agree with you that it is important to “obtain an optimal balance between cardiovascular risk reduction, hemorrhagic risk avoidance, and mitigation of side effects related to lipid-lowering therapy.”