Racial and ethnic differences in trends in dementia prevalence and risk factors in the United States.
Racial and ethnic differences in trends in dementia prevalence and risk factors in the United States.
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DOI：
10.1016/j.trci.2018.08.009
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发表时间：
2018
期刊：
影响因子：
--
通讯作者：
Zissimopoulos JM
中科院分区：
文献类型：
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作者：
Chen C;Zissimopoulos JM
随着时间的推移，美国不同种族/民族的痴呆症患病率差异可能不会缩小。对健康与退休研究（2000 - 2012）的数据进行了分析。痴呆是根据认知和功能测量来确定的。Logistic回归用于量化痴呆与危险因素之间的关系，包括慢性疾病、药物治疗的使用，分别针对白人、黑人和西班牙裔。黑人和白人之间痴呆患病率的差异减小，西班牙裔和白人之间的差异增大。对危险因素进行调整，缩小了差异，但没有消除差异。与没有高血压的人相比，未经治疗的高血压与所有种族/民族的痴呆风险增加有关，而接受治疗的高血压与白人的痴呆风险降低有关。用口服药物治疗糖尿病与痴呆风险增加无关。痴呆症的种族差异可以通过疾病的预防和管理以及促进黑人和西班牙裔人的受教育程度来减少。
Disparities in dementia prevalence across racial/ethnic groups in the United States may not be narrowing over time. Data from Health and Retirement Study (2000 to 2012) were analyzed. Dementia was ascertained based on cognitive, functional measures. Logistic regression was used to quantify association between dementia and risk factors, including chronic conditions, use of drug treatment for them, separately for whites, blacks, and Hispanics. Disparities in dementia prevalence declined between blacks and whites and increased between Hispanics and whites. Adjusting for risk factors reduced but did not eliminate disparities. Compared to no hypertension, untreated hypertension was associated with increased risk of dementia for all racial/ethnic groups while treated hypertension was associated with reduced risk for whites. Diabetes treated with oral drugs was not associated with increased dementia risk. Racial disparities in dementia may be reduced by prevention and management of disease and promoting educational attainment among blacks and Hispanics.