The use Platelet Rich Fibrin in dental implants: A literature review
The use Platelet Rich Fibrin in dental implants: A literature review
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富血小板纤维蛋白在牙种植体中的应用：文献综述
DOI：
10.15761/tit.1000253
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发表时间：
2018
期刊：
影响因子：
--
通讯作者：
C. V. Roman
中科院分区：
文献类型：
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作者：
Vandson Souza Magalhães;R. Ribeiro;José Marcio B. L. do Amaral;A. Pimentel;Lilian Anami Paulim;C. V. Roman
背景：富含血小板的纤维蛋白（PRF）是一种源自人体血液的生物材料，是通过离心机分离获得的血小板浓缩物的一部分。它在医学和牙科中非常常见，用于手术中的恢复和愈合以及组织再生。本文献综述的目的是评估 PRF 在牙科中的使用，特别是在牙种植体的安装中。材料和方法：1997 年至 2018 年间发表的文章在 Pubmed、Scielo 和 Lilacs 数据库中进行了评估。评估了 128 篇文章，其中 18 篇评估了 PRF 的使用并用于本次系统评价。结果：PRF的主要优点和特点是：加速牙科手术特别是种植牙中骨骼和牙龈的瘢痕形成过程；组织再生潜力高； PRF能够将成体干细胞转化为形成骨和牙龈组织的特定细胞；再生组织血管网络的能力。一些研究指出使用 PRF 作为单一填充材料，其他研究仍然表明将 PRF 与其他骨移植材料结合使用。 PRF 还可以用作引导骨再生的膜，其中坚固且有弹性的三维结构充当可饱和屏幕，覆盖并稳定移植材料，保护材料和伤口本身，允许牙龈边缘接近，从而有利于其重新上皮化。结论：我们得出结论，PRF 的应用有很多，但在日常实践中使用其需要了解生物材料、效率和局限性。 *通讯作者：Caio Vinicius G. Roman-Torres，Rua Eneas de Siqueira Neto 教授，地址：340，São Paulo，SP，巴西，电话：+55 11 21418555；电子邮件：cvgrt@hotmail.com
Background: Platelet rich fibrin (PRF) is a biomaterial derived from human blood, part of a platelet concentrate obtained through a centrifuge separating it. Its use is quite common in medicine and dentistry for recovery and healing in surgeries and for tissue regeneration. The aim of the present literature review was to evaluate the use of PRF in dentistry especially in the installation of dental implants. Material and methods: Articles published between 1997 and 2018 were evaluated in Pubmed, Scielo and Lilacs databases. were evaluated 128 articles, of these 18 evaluated the use of PRF and were used in this systematic review. Results: The main advantages and characteristics of PRF are: the acceleration of the cicatricial process of bones and gums in dental surgeries, especially in dental implants; high potential for tissue regeneration; PRF is capable of transforming adult stem cells into specific cells for the formation of bone and gingival tissues; ability to regenerate the tissue vascularization network. Some studies point to the use of PRF as a single fill material, others still show the use of PRF in combination with other bone graft materials. PRF can also be used as a membrane for guided bone regeneration, where the strong and elastic three-dimensional architecture acts as a saturable screen that will cover and stabilize the grafted material, protecting the material and the wound itself, allowing the gingival edges to approach and, consequently, favoring their re-epithelialization. Conclusion: We conclude that the applications of PRF are numerous, but a knowledge of biomaterial, efficiency and limitations are necessary for its use in daily practice. *Correspondence to: Caio Vinicius G. Roman-Torres, Rua Professor Eneas de Siqueira Neto, 340, São Paulo, SP, Brazil, Tel: +55 11 21418555; Email: cvgrt@ hotmail.com