Progress and perspectives in pediatric acute respiratory distress syndrome.
Progress and perspectives in pediatric acute respiratory distress syndrome.
复制标题
DOI：
10.5935/0103-507x.20150035
复制
发表时间：
2015-07
影响因子：
--
通讯作者：
Garcia PC
中科院分区：
文献类型：
--
作者：
Rotta AT;Piva JP;Andreolio C;de Carvalho WB;Garcia PC
急性呼吸窘迫综合征是一种急性发作的疾病，其特征是低氧血症和胸片上的浸润，影响所有年龄的成人和儿童。它是儿科重症监护病房呼吸衰竭的重要原因，并与显著的发病率和死亡率相关。然而，直到最近，急性呼吸窘迫综合征的定义和诊断标准一直集中在成人人群。在这篇文章中，我们回顾了近五十年来急性呼吸窘迫综合征定义的演变，特别关注新的儿科定义。我们还讨论了在儿童急性呼吸窘迫综合征的治疗中实施机械通气策略和使用辅助治疗的建议。
Acute respiratory distress syndrome is a disease of acute onset characterized by hypoxemia and infiltrates on chest radiographs that affects both adults and children of all ages. It is an important cause of respiratory failure in pediatric intensive care units and is associated with significant morbidity and mortality. Nevertheless, until recently, the definitions and diagnostic criteria for acute respiratory distress syndrome have focused on the adult population. In this article, we review the evolution of the definition of acute respiratory distress syndrome over nearly five decades, with a special focus on the new pediatric definition. We also discuss recommendations for the implementation of mechanical ventilation strategies in the treatment of acute respiratory distress syndrome in children and the use of adjuvant therapies.