Frontiers in the Use of Biomarkers of Health in Research on Stress and Aging
Frontiers in the Use of Biomarkers of Health in Research on Stress and Aging
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DOI：
10.1093/geronb/gbq049
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发表时间：
2010-09-01
影响因子：
6.2
通讯作者：
Klein, Laura C.
中科院分区：
文献类型：
--
作者：
Piazza, Jennifer R.;Almeida, David M.;Klein, Laura C.
在压力和衰老的心理学研究中，对反映生理过程客观指标的生物标志物的评估越来越受欢迎。本文综述了神经内分泌和免疫系统的生物标志物，包括与测量和规范性年龄相关变化有关的问题。我们还讨论了如何暴露于压力可以引起这些生物标志物的变化，并提出压力的经验可能会加速这些系统中与年龄相关的下降。我们建议，未来的研究检查身体健康和衰老纳入动态和多变量的方法来评估压力源和生物标志物之间的联系。
Assessment of biomarkers that reflect objective indicators of physiological processes has become increasingly popular in psychological research on stress and aging. The current article reviews biomarkers of the neuroendocrine and immune systems, including issues related to measurement and normative age-related changes. We also discuss how exposure to stressors can provoke changes in these biomarkers and propose that stressful experiences may accelerate age-related declines in these systems. We recommend that future research examining physical health and aging incorporate dynamic and multivariate methods for assessing links between stressors and biomarkers.