Solid-Phase Synthesis of β-Peptoids with Chiral Backbone Substituents Using Reductive Amination
Solid-Phase Synthesis of β-Peptoids with Chiral Backbone Substituents Using Reductive Amination
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DOI：
10.1021/acs.orglett.7b02909
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发表时间：
2017-11-03
期刊：
影响因子：
5.2
通讯作者：
Sando, Shinsuke
中科院分区：
文献类型：
--
作者：
Morimoto, Jumpei;Fukuda, Yasuhiro;Sando, Shinsuke
建立了一种新的β-类肽亚单体合成方法，该方法允许引入手性骨架取代基。描述了在β-碳上具有各种骨架取代基的β-类肽的合成和合成的寡聚物的光谱研究。
A new submonomeric synthetic method of beta-peptoids that allows introduction of chiral backbone substituents is established. The synthesis of beta-peptoids with various backbone substituents on beta-carbons and spectroscopic studies of synthesized oligomers are described.