Is There a Threshold in the Antibacterial Action of Superhydrophobic Surfaces?
Is There a Threshold in the Antibacterial Action of Superhydrophobic Surfaces?
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DOI：
10.1021/acsami.7b11402
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发表时间：
2017-11-15
影响因子：
9.5
通讯作者：
Tserepi, Angeliki
中科院分区：
文献类型：
--
作者：
Ellinas, Kosmas;Kefallinou, Dionysia;Tserepi, Angeliki
抗菌表面的实现是一个重要的科学问题，可以通过使用超疏水表面来解决，减少细菌粘附。然而，关于此类表面的抗菌功效存在一些局限性和相互矛盾的报道。此外，通过最小化粘附来实现抗菌作用并不能确保完全防止细菌。在这里，我们确定了影响超疏水表面抗菌作用的重要因素，强调细菌浓度的作用，并观察浓度上限，高于该浓度阈值任何表面的抗菌作用都会受到损害。最后，我们提出富含金属的超疏水表面作为体外应用的“终极”“混合”抗菌表面。
The realization of antibacterial surfaces is an important scientific problem, which may be addressed by the use of superhydrophobic surfaces, reducing bacterial adhesion. However, there are several limitations and contradicting reports on the antibacterial efficacy of such surfaces. Moreover, achieving antibacterial action through minimization of adhesion does not ensure complete protection against bacteria. Here, we identify the important factors affecting antibacterial action on superhydrophobic surfaces, emphasizing the role of bacterial concentration, and observing an upper concentration threshold above which antibacterial action of any surface is compromised. Finally, we propose metal enriched, superhydrophobic surfaces, as the "ultimate" "hybrid" antibacterial surfaces for in vitro applications.