Effect of Electroacupuncture on Pain Perception and Pain-Related Affection: Dissociation or Interaction Based on the Anterior Cingulate Cortex and S1.
Effect of Electroacupuncture on Pain Perception and Pain-Related Affection: Dissociation or Interaction Based on the Anterior Cingulate Cortex and S1.
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电针对疼痛感知和疼痛相关情感的影响：基于前扣带皮层和 S1 的分离或相互作用
DOI：
10.1155/2020/8865096
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发表时间：
2020
影响因子：
3.1
通讯作者：
Shao X
中科院分区：
文献类型：
--
作者：
Shi Y;Yao S;Shen Z;She L;Xu Y;Liu B;Liang Y;Jiang Y;Sun J;Wu Y;Du J;Zhu Y;Wu Z;Fang J;Shao X
电针能有效地调节痛觉和疼痛相关的负性情绪，但目前尚不清楚电针对感觉和情感的作用是平行的还是分离的、相互作用的。在本研究中，我们观察了前扣带回(ACC)损毁和初级躯体感觉皮层(S1)激活对S1的痛觉、痛相关影响和神经振荡的影响。损毁ACC并不影响痛觉，但减轻了疼痛配对的厌恶。S1的激活增加了痛觉和焦虑行为。无论是否存在ACC病变，电针都可以减轻疼痛感觉。慢性疼痛可能会增加S1脑区的Delta和theta带的振荡活动，而降低α、β和Gamma带的振荡活动。电针干预可抑制α带和β带的振荡活动。这些结果表明，电针可能通过不同的机制减轻慢性疼痛，减轻疼痛感知和减轻疼痛相关的影响。这一证据建立在先前对慢性疼痛和电针治疗的研究结果基础上。
Electroacupuncture (EA) can effectively modulate pain perception and pain-related negative affect; however, we do not know whether the effect of EA on sensation and affect is parallel, or dissociated, interactional. In this study, we observed the effects of the anterior cingulate cortex (ACC) lesion and the primary somatosensory cortex (S1) activation on pain perception, pain-related affection, and neural oscillation in S1. ACC lesions did not affect pain perception but relieved pain-paired aversion. S1 activation increased pain perception and anxious behavior. EA can mitigate pain perception regardless of whether there is an ACC lesion. Chronic pain may increase the delta and theta band oscillatory activity in the S1 brain region and decrease the oscillatory activity in the alpha, beta, and gamma bands. EA intervention may inhibit the oscillatory activity of the alpha and beta bands. These results suggest that EA may mitigate chronic pain by relieving pain perception and reducing pain-related affection through different mechanisms. This evidence builds upon findings from previous studies of chronic pain and EA treatment.
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影响因子：
5.7
作者：
Hsu, Sheng-Feng;Chen, Chien-Yue;Lin, Jaung-Geng
通讯作者：
Lin, Jaung-Geng
影响因子：
5.3
作者：
Huang, Yan;Chen, Lin;Luo, Huan
通讯作者：
Luo, Huan
影响因子：
7.4
作者：
Kaplan, Chelsea M.;Schrepf, Andrew;Harris, Richard E.
通讯作者：
Harris, Richard E.
影响因子：
5.7
作者：
Cavanagh, James F.
通讯作者：
Cavanagh, James F.
影响因子：
3.4
作者：
Kragel PA;LaBar KS
通讯作者：
LaBar KS