Response of the corneal endothelium to cataract surgery.
Response of the corneal endothelium to cataract surgery.
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DOI：
10.1001/archopht.1986.01050200070053
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发表时间：
1986-08
影响因子：
--
通讯作者：
R. O. Schultz;D. Glasser;M. Matsuda;R. Yee;H. Edelhauser
中科院分区：
文献类型：
--
作者：
R. O. Schultz;D. Glasser;M. Matsuda;R. Yee;H. Edelhauser
对白内障囊内摘除(4只眼)、白内障囊外摘除(5只眼)、后房型人工晶状体植入术(13只眼)术后角膜内皮细胞密度、形态和角膜厚度进行连续观察。无论哪种类型的白内障手术，细胞丢失和形态变化(六角形细胞百分比减少，细胞伸长增加，变异系数增加)最大，发生在角膜上段一周内。中央区1个月后也有类似的变化，但次中区的变化很小。内皮细胞密度稳定，角膜所有区域的形态变化在三个月内消失。角膜肿胀在一个月内消退。这两种手术之间的差异只在内皮细胞的上部有所不同，在囊内白内障摘除术后，那里的细胞丢失和形态变化最大。此外，无论是否植入后房型人工晶状体，白内障手术后三个月内皮细胞伤口愈合完全且稳定。
Regional changes in endothelial cell density, morphology, and corneal thickness were serially examined with a specular microscope after intracapsular cataract extraction (four eyes), extracapsular cataract extraction (five eyes), and extracapsular cataract extraction with posterior chamber lens implantation (13 eyes). Regardless of the type of cataract surgery, cell loss and morphologic changes (decreased percentage of hexagonal cells, increased cellular elongation, and increased coefficient of variation) were greatest and occurred within one week in the superior cornea. Similar changes occurred after one month centrally but were minimal inferiorly. Endothelial cell density stabilized, and the morphologic changes resolved within three months in all regions of the cornea. Corneal swelling resolved within one month. Differences between the procedures were noted only in the superior portion of endothelium, where cell loss and morphologic changes were greatest following intracapsular cataract extraction. Also, endothelial wound healing was complete and stable three months after cataract surgery, with or without posterior chamber lens implantation.