Global distribution of Mycobacterium tuberculosis spoligotypes.

Global distribution of Mycobacterium tuberculosis spoligotypes.
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DOI:
10.3201/eid0811.020125
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发表时间:
2002-11
影响因子:
11.8
通讯作者:
Rastogi N
Rastogi N
中科院分区:
医学2区
文献类型:
--
作者:
Filliol I;Driscoll JR;Van Soolingen D;Kreiswirth BN;Kremer K;Valétudie G;Anh DD;Barlow R;Banerjee D;Bifani PJ;Brudey K;Cataldi A;Cooksey RC;Cousins DV;Dale JW;Dellagostin OA;Drobniewski F;Engelmann G;Ferdinand S;Gascoyne-Binzi D;Gordon M;Gutierrez MC;Haas WH;Heersma H;Källenius G;Kassa-Kelembho E;Koivula T;Ly HM;Makristathis A;Mammina C;Martin G;Moström P;Mokrousov I;Narbonne V;Narvskaya O;Nastasi A;Niobe-Eyangoh SN;Pape JW;Rasolofo-Razanamparany V;Ridell M;Rossetti ML;Stauffer F;Suffys PN;Takiff H;Texier-Maugein J;Vincent V;De Waard JH;Sola C;Rastogi N

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我们简要总结了最近对结核分枝杆菌复合体主要分支全球分布的观察结果,结核分枝杆菌复合体是结核病的病原体。这一全球分布是通过对国际分型数据库SpolDB3进行数据挖掘而确定的。该数据库包含来自90多个国家和地区的11,708个临床分离株的模式。11,708个种子型被聚为813个共享型。还检测到1300个孤儿模式(临床分离株显示出独特的SPOLOG型)。
We present a short summary of recent observations on the global distribution of the major clades of the Mycobacterium tuberculosis complex, the causative agent of tuberculosis. This global distribution was defined by data-mining of an international spoligotyping database, SpolDB3. This database contains 11,708 patterns from as many clinical isolates originating from more than 90 countries. The 11,708 spoligotypes were clustered into 813 shared types. A total of 1,300 orphan patterns (clinical isolates showing a unique spoligotype) were also detected.