Vasopressin : principles and properties
Vasopressin : principles and properties
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加压素：原理和特性
DOI：
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发表时间：
1987
期刊：
影响因子：
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通讯作者：
G. Boer
中科院分区：
文献类型：
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作者：
D. Gash;G. Boer
加压素的概念：原理和性质起源于1983年夏天。通过回顾关于加压素的丰富多样的文献，很明显，该领域的快速发展使得很难将从不同科学学科收集的信息综合成加压素生物学作用的一致观点。我们认为有必要对最近的进展进行一系列严格的审查。近十年来，加压素的解剖学、生理学、药理学、分子生物学和行为学研究取得了重大进展。这在很大程度上是由于发现加压素不再仅仅被认为是一种神经垂体激素。我们目前的知识是加压素在神经系统和大脑中合成，也具有轴突信使的作用，尽管加压素在加压素位点之外的这些外周位点中的功能还不清楚。为了编写一份关于脊椎动物最新研究的综述，根据作者的专业知识选择了作者，并要求他们回顾自己的研究领域，包括其他实验室的工作。我们的目的是提供一个更新的明确的参考，这将补充和扩展过去的文本，如神经垂体激素和类似的多肽（实验药理学手册，1968年，第23卷）和垂体及其神经内分泌控制（生理学手册，第7节：第IV卷，1974年）。"
The concept for Vasopressin: Principles and Properties originated during the sum mer of 1983. From reviewing the rich and diverse literature on vasopressin, it became evident that the rapid advancements in this field made it difficult to syn thesize the information gathered from divergent scientific disciplines into a coherent view of the biological role of vasopressin. We perceived the need for a series of critical reviews delineating this recent progress. Over the past decade, major advances have been made in studies of the anatomy, physiology, phar macology, molecular biology, and behavioral activities of vasopressin. This is, in no small measure, due to the finding that vasopressin can no longer be regarded solely as a neurohypophysial hormone. Our present knowledge is that vasopressin is synthesized in also has an axonal messenger role in the nervous system and of the brain, although the functions of vasopressin in these periph sites outside of vasopressin eral sites are not well understood. In order to prepare an overview concentrating on recent studies in vertebrates, authors were selected based on their expertise and asked to review their research area, including the work from other laboratories. It was our intent to provide an updated definitive reference which would complement and extend such past texts as Neurohypophysial Hor mones and Similar Polypeptides (Handbook of Experimental Pharmacology, Vol ume XXIII, 1968) and The Pituitary Gland and Its Neuroendocrine Control (Handbook of Physiology, Section 7: Volume IV, 1974)."