Health-Related Quality of Life in Adults with Metabolic Syndrome: The Korea National Health and Nutrition Examination Survey, 2007-2008
Health-Related Quality of Life in Adults with Metabolic Syndrome: The Korea National Health and Nutrition Examination Survey, 2007-2008
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DOI：
10.1159/000341494
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发表时间：
2012-01-01
影响因子：
3.9
通讯作者：
Kim, Sung Rok
中科院分区：
文献类型：
--
作者：
Lee, Yu-Ji;Woo, Sook Young;Kim, Sung Rok
背景/目的：代谢综合征和受损的健康相关生活质量(HRQOL)之间的联系仍然存在争议。我们在韩国成年人群中调查了代谢综合征本身和HRQL之间的关系。方法：本研究对参加2007年和2008年韩国国民健康和营养检查调查的8941名6 19岁的成年人进行横断面分析。采用EuroQol五维度(EQ-5D)、EQ-5D指数和EQ视觉模拟量表(EQ-VAS)评定患者的生活质量。结果：代谢综合征患病率为26.2%。与没有代谢综合征的参与者相比，有代谢综合征的参与者年龄更大，男性比例更高。此外，患有代谢综合征的参与者更有可能具有较低的教育水平，目前吸烟者，活动受限，以及更频繁的代谢异常和合并症。在简单回归分析中，代谢综合征与基于EQ-5D和EQ VAS的HRQL相关。然而，在调整了EQ-5D的年龄、性别、吸烟状况、收入、教育程度、婚姻状况、肥胖、糖尿病、中风、心脏病和慢性肾脏病史以及EQ-VAS的抑郁史后，代谢综合征与HRQL没有显著关联。结论：调整了社会人口学因素、医学合并症和肥胖等混杂变量后，代谢综合征本身与HRQL受损无关。版权所有(C)2012 S.Karger AG，巴塞尔
Background/Aims: An association between metabolic syndrome and impaired health-related quality of life (HRQoL) is still controversial. We investigated the association between metabolic syndrome in itself and HRQoL in the Korean adult population. Methods: The study is a cross-sectional analysis of 8,941 adults 6 19 years of age who participated in the 2007 and 2008 Korean National Health and Nutrition Examination Survey. EuroQoL five-dimension (EQ-5D), the EQ-5D index and the EQ visual analogue scale (EQ VAS) were used to assess HRQoL. Results: The prevalence of metabolic syndrome was 26.2%. Compared to the participants without metabolic syndrome, those with metabolic syndrome were older and comprised a higher proportion of men. Moreover, participants with metabolic syndrome were more likely to have a lower education level, to be current smokers, to have activity limitation and to have more frequent metabolic abnormalities and comorbidities. Metabolic syndrome was associated with HRQoL based on EQ-5D and EQ VAS in simple regression analysis. However, metabolic syndrome was not significantly associated with HRQoL after adjusting for age, sex, smoking status, income, education level, marital status, obesity, diabetes mellitus, stroke, history of heart disease and chronic kidney disease for EQ-5D, and in addition history of depression for EQ VAS. Conclusion: Metabolic syndrome in itself was not associated with impaired HRQoL after adjusting for confounding variables such as socio-demographic factors, medical comorbidities and obesity. Copyright (C) 2012 S. Karger AG, Basel