Fluid intake restores retinal blood flow early after exhaustive exercise in healthy subjects
Fluid intake restores retinal blood flow early after exhaustive exercise in healthy subjects
复制标题
DOI：
10.1007/s00421-018-3839-6
复制
发表时间：
2018-05-01
影响因子：
3
通讯作者：
Hayashi, Naoyuki
中科院分区：
文献类型：
--
作者：
Ikemura, Tsukasa;Suzuki, Katsuhiko;Hayashi, Naoyuki
目前尚不清楚补液是否能恢复因力竭运动而减少的视网膜血流量。为了研究液体摄入对力竭运动后视网膜血流量的影响，对13名健康男性进行递增负荷自行车运动直到力竭，测量了递增负荷运动前后视网膜下小动脉(ITRA)和颞叶上小动脉(StrA)的血流量。运动后，受试者休息，不喝水(对照条件：CON)或饮用含水的电解质(复水条件：REH)，并进行120min的随访。为了评估体质量，采集静脉血样并计算血浆容量(PV)。试验结束后CON患者的体质量下降[-1.1+/-0.1%(Mean+/-SE)，p<；0.05]。恢复期CON组PV低于REH组。运动后即刻ITRA和StrA血流量较安静时下降(ITRA；-23+/-4%，CON：-30+/-4%，p<；0.05)。在恢复期15分钟，REH组ITRA血流量恢复到基线水平(-9+/-3%，p=0.5)，而CON组ITRA血流量仍减少(-14+/-3%，p<；0.05)。REH组视网膜血流量在15min时高于对照组(2+/-3vs.-5+/-3%，p<；0.05)。本研究结果提示，力竭运动所致的视网膜血流量减少可通过早期补液恢复。
It remains unclear whether rehydration restores retinal blood flow reduced by exhaustive exercise. We investigated the effect of fluid intake on retinal blood flow after exhaustive exercise.Blood flow in the inferior (ITRA) and superior temporal retinal arterioles (STRA) was measured before and after incremental cycling exercise until exhaustion in 13 healthy males. After the exercise, the subjects rested without drinking (control condition: CON) or with drinking an electrolyte containing water (rehydrate condition: REH) and were followed up for a period of 120 min. To assess the hydration state, the body mass was measured, and venous blood samples were collected and plasma volume (PV) was calculated.Body mass decreased in CON after the trial [- 1.1 +/- 0.1% (mean +/- SE), p < 0.05]. PV was lower in CON than in REH during recovery. The ITRA and STRA blood flows decreased immediately after exercise from the resting baseline (ITRA; - 23 +/- 4% in REH and - 30 +/- 4% in CON, p < 0.05). The ITRA blood flow recovered baseline level at 15 min of recovery in REH (- 9 +/- 3%, p = 0.5), but it remained reduced in CON (-14 +/- 3%, p < 0.05). The STRA blood flow was higher in REH than in CON at 15 min (2 +/- 3 vs. - 5 +/- 3%, p < 0.05).The results of this study suggest that the reduction in retinal blood flow induced by exhaustive exercise can be recovered early by rehydration.