Neurogenic and nonneurogenic pain and inflammatory mediators.
Neurogenic and nonneurogenic pain and inflammatory mediators.
复制标题
神经源性和非神经源性疼痛和炎症介质。
DOI：
--
复制
发表时间：
1991
期刊：
影响因子：
--
通讯作者：
J. Weinstein
中科院分区：
文献类型：
--
作者：
J. Weinstein
疼痛不是一种简单的感知。尽管数百万人因此而受苦，数十亿美元被用于试图根除它，但我们只是在理解感知或扭曲我们的痛苦感受所需的非常复杂的相互作用方面处于起步阶段。我们不仅必须继续寻求更好地了解患者对疼痛的宏观印象，而且必须从微观角度观察参与整个疼痛过程的每个细胞。总有一天，我们对分子的理解将为我们提供解开痛苦秘密的手段。自笛卡尔时代以来，我们对疼痛的神经生理学和解剖学的理解已经走过了漫长的道路，但是如果我们要在未来为患者提供更好的治疗方法，我们还有很多工作要做。
Pain is not a simple perception. Although millions of people suffer because of it and billions of dollars are spent trying to eradicate it, we are only in our infancy of understanding the very complex interactions necessary to perceive or distort our feelings of pain. We must continue to seek a better understanding of not only our patients' macroscopic impression of pain, but we must look microscopically at each cell involved in the whole of the pain process. A time will come when our molecular understanding will provide us with the means to unlock the secrets of pain. We have come a long way since the time of Descartes in our understanding of the neurophysiology and anatomy of pain, but we have a great deal more work to do if we are going to provide our patients with better remedies in the future.