The roles of the medial prefrontal cortex and striatum in reputation processing
The roles of the medial prefrontal cortex and striatum in reputation processing
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DOI：
10.1080/17470910903202559
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发表时间：
2010-01-01
影响因子：
2
通讯作者：
Sadato, Norihiro
中科院分区：
文献类型：
--
作者：
Izuma, Keise;Saito, Daisuke N.;Sadato, Norihiro
我们的声誉对我们的日常行为有相当大的影响，被认为是解释利他主义的一个重要概念，利他主义是人类的一种独特特征。此前，有人提出，处理一个人的声誉需要内侧前额叶皮质(MPFC)的声誉表征和纹状体的价值表征。在这里，我们使用功能磁共振成像(FMRI)直接测试了这一想法。受试者在其他人在场或不在场的情况下，参照社会规范披露了他们的行为倾向，这种操纵方式被认为会极大地影响个人对自己声誉的担忧。在自我参照加工过程中，mPFC表现出很强的激活，而且这种活性仅因观察者的存在而增强。此外，当受试者在观察者面前做出反应时，纹状体也被强烈激活。因此，本研究表明，当任务对处理他人如何看待一个人提出了很高的要求时，mPFC和纹状体被自动招募。综上所述，我们的发现表明，mPFC和纹状体在调节人类社会行为方面起着关键作用，这些结果为人类利他主义的神经基础提供了有价值的见解。
How we are viewed by other individualsour reputationhas a considerable influence on our everyday behaviors and is considered an important concept in explaining altruism, a uniquely human trait. Previously it has been proposed that processing one's own reputation requires a reputation representation in the medial prefrontal cortex (mPFC) and a value representation in the striatum. Here, we directly tested this idea using functional magnetic resonance imaging (fMRI). Subjects disclosed their behavioral tendencies with reference to social norms in the presence or absence of other people, a manipulation that is known to greatly affect an individual's concern for their reputation. The mPFC showed strong activation during self-referential processing, and this activity was enhanced by the mere presence of observers. Moreover, the striatum was also strongly activated when subjects responded in front of observers. Thus, the present study demonstrated that the mPFC and striatum were automatically recruited when the task placed a high demand on processing how one is viewed by others. Taken together, our findings suggest that the mPFC and the striatum play a key role in regulating human social behaviors, and these results provide valuable insight into the neural basis of human altruism.