RESIDUES OF OXOLINIC ACID AND OXYTETRACYCLINE IN FISH AND SEDIMENTS FROM FISH FARMS
RESIDUES OF OXOLINIC ACID AND OXYTETRACYCLINE IN FISH AND SEDIMENTS FROM FISH FARMS
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DOI：
10.1016/0044-8486(91)90281-b
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发表时间：
1991-09-01
期刊：
影响因子：
4.5
通讯作者：
BYLUND, G
中科院分区：
文献类型：
--
作者：
BJORKLUND, HV;RABERGH, CMI;BYLUND, G
研究了5个养鱼场化学治疗后鱼体和沉积物中氧杂环酸和土霉素的残留情况。 与土霉素相比，恶喹酸更好地吸收，更快地从处理过的鱼排出。 在加药鱼围栏下的沉积物中发现土霉素的持久性浓度为0.8-6.3 μ g/g。 在鱼处理后5天，在沉积物中测得的恶喹酸水平为0.05-0.2 μ g/g。 与土霉素相比，恶喹酸在养鱼场沉积物中表现出更快的抗菌活性丧失。 从处理的鱼和鱼围栏下的沉积物中分离出对土霉素具有抗性的鱼病原菌。 本研究未发现对恶喹酸产生耐药性的鱼类病原菌。
The residues of oxolonic acid and oxytetracycline were studied in fish and sediments from five fish farms after chemotherapy of the farmed fish. Compared to oxytetracycline, oxolinic acid was better absorbed and faster excreted from the treated fish. Oxytetracycline was found persistent in concentrations of 0.8-6.3-mu-g/g in the sediments under the medicated fish pens. Oxolinic acid levels of 0.05-0.2-mu-g/g were measured in the sediments for 5 days after the treatment of the fish. Compared to oxytetracycline, oxolinic acid showed a faster loss of antibacterial activity in the fish farm sediments. Fish pathogenic bacteria resistant to oxytetracycline were isolated from the treated fish and from the sediments under fish pens. No fish pathogenic bacteria resistant to oxolinic acid were found in this study.