Regional differences in mechanical and material properties of femoral head cancellous bone in health and osteoarthritis
Regional differences in mechanical and material properties of femoral head cancellous bone in health and osteoarthritis
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DOI：
10.1007/s00223-001-2102-y
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发表时间：
2002-09-01
影响因子：
4.2
通讯作者：
Sharp, CA
中科院分区：
文献类型：
--
作者：
Brown, SJ;Pollintine, P;Sharp, CA
骨关节炎（OA）是一种常见于老年人群的衰弱性疾病。在这项研究中，我们已经确定了松质骨芯的力学和材料性能，从两个不同的负载区域的股骨头，从健康受试者和那些终末期骨关节炎。在压缩测试之前测定密度特性，以测定杨氏模量（E-C）和屈服强度，之后将骨粉末化以分析胶原和矿物质含量。在OA和正常松质骨中。上级骨密度（BMDv）、表观密度（rho（A））、E-C和σ（y）系统性地大于下级（P
Osteoarthritis (OA) is a debilitating condition common among the aging population. In this study we have determined mechanical and material properties of cancellous bone cores from two differently loaded regions of femoral heads obtained from healthy subjects and those with end-stage osteoarthritis. Densitometric properties were determined prior to compression testing for Young's modulus (E-C) and yield strength after which bones were powdered for analysis of collagen and mineral content. In both OA and normal cancellous bone. volumetric bone mineral density (BMDv), apparent density (rho(A)), E-C, and sigma(y), were systematically greater in the superior than in the inferior region (P