Depression and distress predict time to cardiovascular disease in dementia caregivers
Depression and distress predict time to cardiovascular disease in dementia caregivers
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DOI：
10.1037/0278-6133.26.5.539
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发表时间：
2007-09-01
影响因子：
4.2
通讯作者：
Schulz, Richard
中科院分区：
文献类型：
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作者：
Mausbach, Brent T.;Patterson, Thomas L.;Schulz, Richard
目的：本研究以643名痴呆症家庭照顾者为样本，评估了患者问题行为带来的抑郁症状和痛苦对心血管疾病(CVD)诊断的影响。设计：采用纵向前瞻性设计。在18个月的时间里，在基线上没有心血管疾病诊断的照顾者分别在6个月、12个月和18个月的随访中被评估为心血管疾病的发生。主要观察指标：CVD发病天数为主要结局。结果：在整个研究过程中，32名参与者(5%)报告了心血管疾病的诊断。在调整了社会人口和健康因素(例如，高血压、年龄、吸烟史)后，更严重的抑郁症状(p=.040)和患者问题行为带来的痛苦(p=.034)是CVD诊断时间的重要预测因素。结论：本研究表明，抑郁症状的增加和对患者问题行为(即痛苦)的反应可能会增加照顾者经历负面健康后果的风险，特别是心血管疾病。
Objective: This study assessed the impact of depressive symptoms and distress from patient problem behaviors on time to developing a diagnosis of cardiovascular disease (CVD) in a sample of 643 dementia family caregivers. Design: A longitudinal, prospective design was used. Over an 18-month period, caregivers free from a CVD diagnosis at baseline were assessed at 6, 12, and 18-month follow-ups for the onset of CVD. Main Outcome Measures: Days to the onset of CVD was the primary outcome. Results: Over the length of the study, 32 participants (5%) reported a diagnosis of CVD. After adjusting for sociodemographic and health factors (e.g., high blood pressure, age, smoking history), greater depressive symptoms (p =.040) and distress from patient problem behaviors (p =.034) were significant predictors of time to CVD diagnosis. Conclusion: This study suggests that increased depressive symptoms and reaction to patient problem behaviors (i.e., distress) may increase caregivers' risk for experiencing negative health outcomes, specifically CVD.