How many children remain fracture-free during growth? A longitudinal study of children and adolescents participating in the Dunedin Multidisciplinary Health and Development Study
How many children remain fracture-free during growth? A longitudinal study of children and adolescents participating in the Dunedin Multidisciplinary Health and Development Study
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DOI：
10.1007/s001980200137
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发表时间：
2002-01-01
影响因子：
4
通讯作者：
Goulding, A
中科院分区：
文献类型：
--
作者：
Jones, IE;Williams, SM;Goulding, A
虽然关于生长过程中骨折的发生率和模式知道得很多，但关于有多少儿童反复骨折以及有多少儿童在生长过程中没有骨折的信息很少。达尼丁多学科健康与发展研究是一个出生队列，其成员在整个成长过程中(5、7、9、11、13、15和18岁)定期接受关于包括骨折在内的伤害的询问，这为回答这些问题提供了一个独特的机会。生命表分析显示，大约一半的儿童在整个生长过程中没有骨折[女孩60.1%(95%可信区间54.7-65.0)，男孩49.3%(95%可信区间44.0-54.4)]。对于每个阶段的参与者，有601名成员到18岁(5岁时看到的61.1%)都有骨折史的数据。在这601名参与者中，291人报告了498处骨折，其中172处为单一骨折，119处以上骨折(15.8%为女孩，23.4%为男孩)。最常见的骨折部位是手腕/前臂(占所有骨折的24.1%)。我们的结论是，尽管骨折是儿童时期常见的不良事件，但所有儿童中有一半在整个成长过程中没有骨折。
While much is known regarding the incidence and pattern of fractures during growth, information is sparse as to how many children fracture repeatedly and how many remain fracture-free during growth. The Dunedin Multidisciplinary Health and Development Study, a birth cohort, whose members were questioned regularly throughout growth (at ages 5, 7, 9, 11, 13, 15 and 18 years) concerning injuries including fractures, has provided a unique opportunity to answer these questions. Life-table analysis showed that approximately half the children remained fracture-free throughout growth [girls 60.1%, (95% CI 54.7-65.0) and boys 49.3% (95% CI 44.0-54.4)]. Data on fracture history, for participants seen at every phase, was available for 601 members through to the age of 18 years (61.1% of the cohort seen at age 5 years). Two hundred and ninety-one of these 601 participants reported 498 fractures, with 172 sustaining a single fracture, and 119 more than one fracture (15.8% girls and 23.4% boys). The most common site of fracture was the wrist/forearm (24.1% of all fractures). We conclude that although bone fractures are a common adverse event in childhood, half of all children remain fracture-free throughout growth.