The Vitamin D Endocrine System and Its Therapeutic Potential
The Vitamin D Endocrine System and Its Therapeutic Potential
复制标题
维生素 D 内分泌系统及其治疗潜力
DOI:
--
复制
发表时间:
1996
期刊:
影响因子:
--
通讯作者:
H. DeLuca
中科院分区:
文献类型:
--
作者:
R. Ettinger;H. DeLuca
Publisher Summary This chapter is devoted to describing the vitamin D endocrine system, how the active hormonal form of vitamin D works, and the potential for treatment of a variety of diseases, ranging from metabolic bone diseases to such diverse disorders as psoriasis and cancer. With the discovery of the activation of the vitamin D molecule has come the application of the metabolites of vitamin D and its analogues to human disease. The discovery of the vitamin D receptor in tissues has resulted in the discovery of new functions of vitamin D, as its involvement in the differentiation and development of the monocyte from the promyelocyte. A further detailed analysis of the role of 1,25-Dihydroxyvitamin D 3 in initiating transcription of target genes will yield new information that will be of value not only in understanding these complex systems but in providing guidance to maximize treatment of disease.
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DOI:
--
发表时间:
1983
期刊:
The Journal of biological chemistry
影响因子:
--
作者:
Reeve,L;Tanaka,Y;DeLuca,HF
通讯作者:
DeLuca,HF
影响因子:
4.2
作者:
道脇幸博
通讯作者:
道脇幸博
影响因子:
2.9
作者:
Perlman,K;Kutner,A;Prahl,J;Smith,C;Inaba,M;Schnoes,HK;DeLuca,HF
通讯作者:
DeLuca,HF
影响因子:
13.8
作者:
Smith,EL;Pincus,SH;Donovan,L;Holick,MF
通讯作者:
Holick,MF
DOI:
10.1016/0304-4165(90)90044-w
发表时间:
1990
期刊:
Biochimica et biophysica acta
影响因子:
--
作者:
Mandel,ML;Swartz,SJ;Ghazarian,JG
通讯作者:
Ghazarian,JG