Motor output evoked by subsaccadic stimulation of primate frontal eye fields
Motor output evoked by subsaccadic stimulation of primate frontal eye fields
复制标题
DOI：
10.1073/pnas.0911902107
复制
发表时间：
2010-03-30
影响因子：
11.1
通讯作者：
Cushing, Sharon L.
中科院分区：
文献类型：
--
作者：
Corneil, Brian D.;Elsley, James K.;Cushing, Sharon L.
In addition to its role in shifting the line of sight, the oculomotor system is also involved in the covert orienting of visuospatial attention. Causal evidence supporting this premotor theory of attention, or oculomotor readiness hypothesis, comes from the effect of subsaccadic threshold stimulation of the oculomotor system on behavior and neural activity in the absence of evoked saccades, which parallels the effects of covert attention. Here, by recording neck-muscle activity from monkeys and systematically titrating the level of stimulation current delivered to the frontal eye fields (FEF), we show that such subsaccadic stimulation is not divorced from immediate motor output but instead evokes neck-muscle responses at latencies that approach the minimal conduction time to the motor periphery. On average, neck-muscle thresholds were similar to 25% lower than saccade thresholds, and this difference is larger for FEF sites associated with progressively larger saccades. Importantly, we commonly observed lower neck-muscle thresholds even at sites evoking saccades
