Poor drug compliance in an adolescent with leukemia.
Poor drug compliance in an adolescent with leukemia.
复制标题
患有白血病的青少年的药物依从性差。
DOI：
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发表时间：
1981
期刊：
影响因子：
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通讯作者：
S. Lansky
中科院分区：
文献类型：
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作者：
S. D. Smith;N. Cairns;J. Sturgeon;S. Lansky
儿科患者服药依从性差是一个令人沮丧的问题，因为它很常见，很难记录，也很难改变。这份报告描述了一名青少年，他被发现在接受急性淋巴细胞白血病的治疗时不遵守规定。17Kgs试验显示三次强的松治疗不顺从--第三次阻止了重新诱导的尝试。进行了心理测试以评估可能导致这种不遵从性的因素。这名患者被发现具有低焦虑、过度敌意、边缘智力和一种命运已注定的感觉。通过对基础疾病进行额外的咨询和教育，尝试了干预治疗，但没有成功。药物依从性最终只有通过住院才能实现。与药物依从性差相关的心理因素和临床情况的识别进行了讨论。
Poor drug compliance in pediatric patients is a frustrating problem for it is common, difficult to document, and difficult to change. This report describes an adolescent who was found to be noncompliant in taking his therapy for acute lymphoblastic leukemia. 17kgs assay showed noncompliance with prednisone therapy three times--the third episode thwarting a reinduction attempt. Psychological testing was performed to assess factors that may have contributed to this noncompliance. This patient was found to have low anxiety, excess hostility, borderline intelligence, and a feeling that his fate was predetermined. Intervention therapy was attempted by additional counseling and education about the basic disease, but this was unsuccessful. Drug compliance was eventually achieved only through hospitalization. Identification of psychological factors and clinical situations associated with poor drug compliance is discussed.