Antigenic variation of surface proteins of Borrelia species.

Antigenic variation of surface proteins of Borrelia species.
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疏螺旋体属表面蛋白的抗原变异。

DOI:
10.1093/cid/10.supplement_2.s399
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发表时间:
1988
期刊:
Reviews of infectious diseases
影响因子:
--
通讯作者:
Barbour,AG
Barbour,AG
中科院分区:
--
文献类型:
--
作者:
Barbour,AG

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During relapsing fever, the etiologic spirochetes employ antigenic variation to avoid early immune clearance. In Borrelia hermsii, an agent of tick-borne relapsing fever, a switch in serotype is associated with a change in the predominant protein on the surface of the cells. The variable major proteins differ from one another in primary structure along their lengths. Genes encoding the different variable major proteins can be found in both "silent" and "active" environments. At the active site the gene is expressed; at the silent site the gene appears to be in storage. In variant cells, which express the new serotype-specific surface protein in a population, a gene from a silent site has replaced the previously sitting gene at the active site through transposition.
赫氏疏螺旋体的抗原变异。
DOI: 10.1084/jem.156.5.1297
发表时间: 1982-11-01
影响因子: 15.3
作者:
Stoenner, H G;Dodd, T;Larsen, C
通讯作者: Larsen, C
DOI: 10.1084/jem.158.6.2127
发表时间: 1983-12-01
期刊: The Journal of experimental medicine
影响因子: --
作者:
Barbour AG;Barrera O;Judd RC
通讯作者: Judd RC
赫氏疏螺旋体的可变主要蛋白
DOI: --
发表时间: 1982
影响因子: 15.3
作者:
A. Barbour;S. L. Tessier;H. Stoenner
通讯作者: H. Stoenner