World Gastroenterology Organization Practice Guidelines for the Diagnosis and Management of IBD in 2010

World Gastroenterology Organization Practice Guidelines for the Diagnosis and Management of IBD in 2010
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DOI:
10.1002/ibd.21048
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发表时间:
2010-01-01
影响因子:
4.9
通讯作者:
Watermeyer, Gillian
Watermeyer, Gillian
中科院分区:
医学2区
文献类型:
--
作者:
Bernstein, Charles N.;Fried, Michael;Watermeyer, Gillian

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炎症性肠病(IBD)代表一组特发性、慢性、炎症性肠道病症。它的两个主要疾病类别是:克罗恩病(CD)和溃疡性结肠炎(UC),这两种疾病的特点是重叠和不同的临床和病理特征。过去,这些疾病在发达国家最为明显,但近几十年来,它们在发展中国家的流行率逐渐上升。这在诊断和管理方面提出了独特的问题,在文献或现有的指南中几乎没有提到。根据投诉的性质,诊断IBD或评估疾病活动的调查将有所不同,并且还将受到可能模拟IBD的其他条件的地理差异的影响。类似地,治疗根据所治疗疾病的表型和可用资源而变化。因此,世界胃肠病学组织已经制定了使用级联方法诊断和治疗IBD的指南,以说明世界各国资源的变化。
Inflammatory bowel disease (IBD) represents a group of idiopathic, chronic, inflammatory intestinal conditions. Its two main disease categories are: Crohn's disease (CD) and ulcerative colitis (UC), which feature both overlapping and distinct clinical and pathological features. While these diseases have, in the past, been most evident in the developed world, their prevalence in the developing world has been gradually increasing in recent decades. This poses unique issues in diagnosis and management which have been scarcely addressed in the literature or in extant guidelines. Depending on the nature of the complaints, investigations to diagnose either form of IBD or to assess disease activity will vary and will also be influenced by geographic variations in other conditions that might mimic IBD. Similarly, therapy varies depending on the phenotype of the disease being treated and available resources. The World Gastroenterology Organization has, accordingly, developed guidelines for diagnosing and treating IBD using a cascade approach to account for variability in resources in countries around the world.