A Mosquito-Borne Disease Model with Non-exponentially Distributed Infection and Treatment Stages

A Mosquito-Borne Disease Model with Non-exponentially Distributed Infection and Treatment Stages
复制标题

具有非指数分布感染和治疗阶段的蚊媒疾病模型

DOI:
10.1007/s10884-020-09863-2
复制
发表时间:
2020
影响因子:
1.3
通讯作者:
Grogan, M.
Grogan, M.
中科院分区:
数学3区
文献类型:
--
作者:
Feng, Z.;Gurski, K. F.;Prosper, O.;Teboh-Ewungkem, M. I.;Grogan, M.

文献摘要

参考文献

被引文献

相似文献

大多数蚊媒疾病的流行病学模型假定疾病阶段的停留时间服从指数分布,以简化模型的建立和分析。然而,这些模型不能准确描述宿主内药物浓度和病原体载量之间的相互作用。为了改善这一点,我们建立了一个模型,通过考虑不同疾病阶段的任意分布的寄宿。该模型采用了两种公认的等价方法:积分方程组和偏微分方程组。模型的分析包括平衡解的存在性和稳定性,它们取决于控制再生次数是小于还是大于1。当一般分布被伽马分布取代时,积分方程组可以简化为一个常微分方程组,它具有一些非平凡的特征,只有疾病阶段的非指数分布才能捕捉到这些特征。
Most epidemiological models for mosquito-borne disease assume exponentially distributed residence times in disease stages in order to simplify the model formulation and analysis. However, these models do not allow for accurate description of the interaction between drug concentration and pathogen load within hosts. To improve this, we formulate a model by considering arbitrarily distributed sojourn for various disease stages. The model formulation is presented using two proven equivalent approaches: integral equations and partial differential equations. Analysis of the model includes the existence of equilibrium solutions and stability, which are shown to be dependent on whether the control reproduction numberis less or greater than 1. It is also shown that, when the general distributions are replaced by gamma distributions, the system of integral equations can be reduced to a system of ODEs, which has some non-trivial characteristics which are only captured by non-exponential distributions for disease stages.
DOI: 10.1186/1471-2458-14-s2-s3
发表时间: 2014
期刊: BMC public health
影响因子: 4.5
作者:
de-Graft Aikins A;Kushitor M;Koram K;Gyamfi S;Ogedegbe G
通讯作者: Ogedegbe G
DOI: 10.1073/pnas.1006113108
发表时间: 2011-01-04
影响因子: 11.1
作者:
Saralamba, Sompob;Pan-Ngum, Wirichada;White, Lisa J.
通讯作者: White, Lisa J.
恶性疟原虫的向量内数学模型以及不完全受精对最佳配子细胞性别比的影响。
DOI: 10.1016/j.jtbi.2009.12.017
发表时间: 2010
影响因子: 2
作者:
M. Teboh;T. Yuster
通讯作者: T. Yuster
DOI: 10.1007/978-1-4939-2782-1
发表时间: 2015
期刊: --
影响因子: --
作者:
T. Jackson;A. Radunskaya
通讯作者: T. Jackson;A. Radunskaya
DOI: 10.1137/0140001
发表时间: 1981-01-01
影响因子: 1.9
作者:
HETHCOTE, HW;STECH, HW;VANDENDRIESSCHE, P
通讯作者: VANDENDRIESSCHE, P