A Mosquito-Borne Disease Model with Non-exponentially Distributed Infection and Treatment Stages
A Mosquito-Borne Disease Model with Non-exponentially Distributed Infection and Treatment Stages
复制标题
具有非指数分布感染和治疗阶段的蚊媒疾病模型
DOI:
10.1007/s10884-020-09863-2
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发表时间:
2020
影响因子:
1.3
通讯作者:
Grogan, M.
中科院分区:
文献类型:
--
作者:
Feng, Z.;Gurski, K. F.;Prosper, O.;Teboh-Ewungkem, M. I.;Grogan, M.
Most epidemiological models for mosquito-borne disease assume exponentially distributed residence times in disease stages in order to simplify the model formulation and analysis. However, these models do not allow for accurate description of the interaction between drug concentration and pathogen load within hosts. To improve this, we formulate a model by considering arbitrarily distributed sojourn for various disease stages. The model formulation is presented using two proven equivalent approaches: integral equations and partial differential equations. Analysis of the model includes the existence of equilibrium solutions and stability, which are shown to be dependent on whether the control reproduction numberis less or greater than 1. It is also shown that, when the general distributions are replaced by gamma distributions, the system of integral equations can be reduced to a system of ODEs, which has some non-trivial characteristics which are only captured by non-exponential distributions for disease stages.
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影响因子:
4.5
作者:
de-Graft Aikins A;Kushitor M;Koram K;Gyamfi S;Ogedegbe G
通讯作者:
Ogedegbe G
DOI:
10.1073/pnas.1006113108
发表时间:
2011-01-04
影响因子:
11.1
作者:
Saralamba, Sompob;Pan-Ngum, Wirichada;White, Lisa J.
通讯作者:
White, Lisa J.
影响因子:
2
作者:
M. Teboh;T. Yuster
通讯作者:
T. Yuster
DOI:
10.1007/978-1-4939-2782-1
发表时间:
2015
期刊:
--
影响因子:
--
作者:
T. Jackson;A. Radunskaya
通讯作者:
T. Jackson;A. Radunskaya
影响因子:
1.9
作者:
HETHCOTE, HW;STECH, HW;VANDENDRIESSCHE, P
通讯作者:
VANDENDRIESSCHE, P