Relation between early motor delay and later communication delay in infants at risk for autism
Relation between early motor delay and later communication delay in infants at risk for autism
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DOI：
10.1016/j.infbeh.2012.07.019
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发表时间：
2012-12-01
影响因子：
2.1
通讯作者：
Landa, R. J.
中科院分区：
文献类型：
--
作者：
Bhat, A. N.;Galloway, J. C.;Landa, R. J.
背景：运动发育迟缓在后来发展为自闭症谱系障碍(ASDS)的婴幼儿的回顾性研究中已有报道。目的：在这项研究中，我们前瞻性地比较了ASDS高危队列；患有自闭症儿童的婴儿兄弟姐妹(AU SIBS)和低风险典型发育(LR)婴儿的大运动发育。方法：使用标准化的运动测量工具，艾伯塔省婴儿运动量表(AIMS)，在3个月和6个月时观察24个AU同胞和24个LR婴儿。此外，作为一项更大规模研究的一部分，AU同胞还接受了一项追踪评估，以确定18个月时的运动和沟通能力。结果：在3个月和6个月时，AU同胞中表现出运动障碍的人数明显多于LR婴儿，大多数AU同胞表现出早期运动障碍和较晚的沟通障碍。限制：样本量小，随访有限。结论：AU同胞中早期运动障碍比LR婴儿更常见。在67-73%的AU同胞中，后来出现了沟通延迟，他们出现了早期的运动延迟。总体而言，早期运动障碍可能预示着自闭症风险儿童未来的沟通障碍。(C)2012 Elsevier Inc.保留所有权利
Background: Motor delays have been reported in retrospective studies of young infants who later develop Autism Spectrum Disorders (ASDs).Objective: In this study, we prospectively compared the gross motor development of cohort at risk for ASDs; infant siblings of children with ASDs (AU sibs) to low risk typically developing (LR) infants.Methods: 24 AU sibs and 24 LR infants were observed at 3 and 6 months using a standardized motor measure, the Alberta Infant Motor Scale (AIMS). In addition, as part of a larger study the AU sibs also received a follow-up assessment to determine motor and communication performance at 18 months using the Mullen Scales of Early Learning.Results: Significantly more AU sibs showed motor delays at 3 and 6 months than LR infants The majority of the AU sibs showed both early motor delays and later communication delays.Limitations: Small sample size and limited follow-up.Conclusions: Early motor delays are more common in AU sibs than LR infants. Communication delays later emerged in 67-73% of the AU sibs who had presented with early motor delays. Overall, early motor delays may be predictive of future communication delays in children at risk for autism. (C) 2012 Elsevier Inc. All rights reserved