Erectile function in male rats after lesions in the lateral paragigantocellular nucleus
Erectile function in male rats after lesions in the lateral paragigantocellular nucleus
复制标题
外侧副巨细胞核损伤后雄性大鼠的勃起功能
DOI：
10.1016/s0304-3940(99)00070-1
复制
发表时间：
1999
影响因子：
2.5
通讯作者：
Benjamin D Sachs
中科院分区：
文献类型：
--
作者：
Yian;Benjamin D Sachs
在之前对大鼠的研究中，髓质外侧副巨细胞核（LPGi）的损伤促进了反射性勃起和射精的表现。本研究试图通过确定 LPGi 损伤是否也会在交配期间和雄性暴露于难以接近的雌性期间促进勃起，即非接触性勃起（NCE）来复制和扩展这些发现。正如预期的那样，具有 LPGi 损伤的男性 (n = 10) 比具有假损伤的男性 (n = 8) 具有更高的反射性勃起发生率，并且在交配过程中，LPGi 损伤的男性在射精前需要更少的插入。然而，这些病变并没有改变交配插入率（勃起功能的部分衡量标准），也没有改变 NCE 的发生率、潜伏期或数量。需要更直接的勃起测量来确定 LPGi 在某些勃起环境中是否不存在对性反射的抑制作用，或者其在某些情况下的作用是否太小而无法在行为测量中表现出来。
In previous research on rats, lesions of the lateral paragigantocellular nucleus (LPGi) in the medulla have facilitated the display of reflexive erection and ejaculation. The present research sought to replicate and extend these findings by determining whether LPGi lesions would also promote erection during copulation and during exposure of the male to inaccessible females, i.e., non-contact erections (NCEs). As expected, males with LPGi lesions (n=10) had a greater incidence of reflexive erection than males with sham lesions (n=8), and during copulation LPGi-damaged males required fewer intromissions before ejaculation. However, the lesions did not change the copulatory intromission ratio, a partial measure of erectile function, nor did they change the incidence, latency, or number of NCEs displayed. More direct measures of erection will be necessary to determine whether the inhibitory role of LPGi on sexual reflexes is absent in some erectile contexts, or whether its role in some contexts is too small to be evident in behavioral measures.