Preoperative In-Hospital Rehabilitation Improves Physical Function in Patients with Pancreatic Cancer Scheduled for Surgery
Preoperative In-Hospital Rehabilitation Improves Physical Function in Patients with Pancreatic Cancer Scheduled for Surgery
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DOI：
10.1620/tjem.251.279
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发表时间：
2020-08-01
影响因子：
2.2
通讯作者：
Yamaue, Hiroki
中科院分区：
文献类型：
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作者：
Mikami, Yukio;Kouda, Ken;Yamaue, Hiroki
癌症患者术前身体功能低下与术后并发症有关；然而，目前还没有关于胰腺癌患者术前院内康复对术前身体功能的益处的报道。因此，这项研究的目的是定量地确定在理疗师的监督下提供的术前住院康复对胰腺癌患者术前身体功能的影响。研究对象为26例患者(男性15例，女性11例；年龄71.2±-8.5岁，范围51~87岁)，包括4例接受术前化疗的胰腺癌患者。术前11.9±5.1天进行肌肉力量训练和有氧运动。在康复方案实施前后分别进行心肺运动试验、6分钟步行距离和功能独立性测试。我们还调查了康复方案与术后并发症发生率的关系。所有26名研究患者都完成了术前康复计划，没有发现任何不良事件。康复治疗后心肺运动试验的最大摄氧量和6分钟步行距离显著增加。功能独立性测量分数在整个干预过程中保持不变。术后无伤口感染、精神错乱、深静脉血栓形成或呼吸道并发症。在理疗师的监督下，院内的术前康复显着改善了胰腺癌患者的身体功能，并维持了身体活动。这样的改善可能有助于预防严重的术后并发症，从而产生更好的结果。
Low preoperative physical function in cancer patients is associated with postoperative complications; however, there have been no reports on the benefits of in-hospital preoperative rehabilitation on preoperative physical function in patients with pancreatic cancer. Therefore, the aim of this study was to quantitatively determine the effects of preoperative in-hospital rehabilitation provided under the supervision of a physiotherapist, on preoperative physical function in patients with pancreatic cancer. The study subjects were 26 patients (15 males, 11 females; age 71.2 +/- 8.5 years, range: 51-87 years), including four patients with preoperative chemotherapy, scheduled for surgery for pancreatic cancer. Muscle strengthening exercises and aerobic exercises were conducted 11.9 +/- 5.1 days prior to surgery. Cardiopulmonary exercise testing, 6-minute walk distance, and the Functional Independence Measure score were measured before and after the rehabilitation program. We also investigated the relation between the rehabilitation program and incidence of postoperative complications. All 26 study patients completed the preoperative rehabilitation program and no adverse events were noted. Peak oxygen uptake during cardiopulmonary exercise testing and 6-minute walk distance increased significantly after the rehabilitation program. The Functional Independence Measure score remained constant throughout the intervention. No wound infection, delirium, deep vein thrombosis, or respiratory complications were encountered postoperatively. In-hospital preoperative rehabilitation under the supervision of a physiotherapist significantly improved physical function and maintained physical activity in patients with pancreatic cancer. Such improvements may contribute toward preventing serious postoperative complications, resulting in better outcomes.