Transport calculations of depth-dose distributions for gadolinium neutron capture therapy.
Transport calculations of depth-dose distributions for gadolinium neutron capture therapy.
复制标题
钆中子俘获疗法深度剂量分布的传输计算。
DOI：
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发表时间：
1992
影响因子：
3.5
通讯作者：
T. Matsumoto
中科院分区：
文献类型：
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作者：
T. Matsumoto
深度剂量分布计算热中子和超热中子注量和捕获伽马射线剂量率使用二维中子耦合伽马射线输运代码（DOT 3.5）的钆中子捕获治疗。结果表明：（i）在放置于水模表面附近的含5000 PPM钆的模拟肿瘤中，热中子注量率为1.5 × 10（9）cm-2 s-1时，捕获γ射线剂量率为10戈伊h-1，（ii）深部肿瘤可用超热中子治疗，和（iii）钆中子俘获治疗似乎实现了与硼中子俘获治疗相当的剂量分布。
Depth-dose distributions were calculated for thermal and epithermal neutron fluence and capture gamma ray dose rates using a two-dimensional neutron-coupled gamma-ray transport code (DOT 3.5) for gadolinium neutron capture therapy. The results show that (i) a capture gamma-ray dose rate of 10 Gy h-1 was obtained with a thermal neutron fluence rate of 1.5 x 10(9) cm-2 s-1 in a simulated tumour containing 5000 PPM gadolinium placed near the surface of a water phantom, (ii) deep-seated tumours may be treated with epithermal neutrons, and (iii) gadolinium neutron capture therapy appears to achieve comparable dose distributions to those of boron neutron capture therapy.