RISK OF PREMENOPAUSAL BREAST-CANCER AND USE OF ELECTRIC BLANKETS
RISK OF PREMENOPAUSAL BREAST-CANCER AND USE OF ELECTRIC BLANKETS
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DOI：
10.1093/oxfordjournals.aje.a117204
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发表时间：
1994-12-01
影响因子：
5
通讯作者：
GRAHAM, S
中科院分区：
文献类型：
--
作者：
VENA, JE;FREUDENHEIM, JL;GRAHAM, S
据估计，电热毯的使用会显著增加60 Hz电磁场的背景暴露，并被假设会增加乳腺癌的风险。从1986年到1991年，作者在纽约州西部对绝经前妇女进行了一项病例对照研究，调查了使用电热毯作为乳腺癌危险因素的情况。共调查了290例绝经前乳腺癌患者和289例年龄匹配的随机选择的社区对照，询问他们在过去10年中使用电热毯的情况，包括季节使用频率和使用方式。在调整了年龄、教育和其他危险因素后，在过去10年中任何时候使用电热毯的优势比（40%的病例和37%的对照）为1.18（95%置信区间（CI）0.83-1.68）。估计的风险并没有不同的剂量反应方式为多年的电热毯使用。季节性每日使用与不使用相关的风险为1.27（95%CI 0.86-1.88）。报告夜间使用毯子的人患乳腺癌的风险为1.43（95%CI 0.94-2.17）。然而，在过去10年中，那些报告在季节中每天使用，连续整夜使用的风险为1.10（95% CI 0.59-2.05）。这些发现并不支持使用电热毯与乳腺癌风险增加有关的假设。通过对更多高暴露个体进行改进措施并量化总电磁场暴露的研究可能会澄清与此类暴露相关的乳腺癌风险的不确定性。
Electric blanket use, estimated to significantly increase background exposure to 60-Hz electromagnetic fields, has been hypothesized to increase breast cancer risk. From 1986 to 1991 in western New York State, the authors investigated the use of electric blankets as a risk factor for breast cancer in a case-control study of premenopausal women. A total of 290 premenopausal breast cancer cases and 289 age-matched randomly selected community controls were queried in regard to their use of electric blankets in the previous 10 years, including frequency of use in season and mode of use. After adjusting for age, education, and other risk factors, the odds ratio for use of an electric blanket at any time in the previous 10 years (40% of cases and 37% of controls) was 1.18 (95% confidence interval (Cl) 0.83-1.68). Estimates of risk did not differ in a dose-response fashion for number of years of electric blanket use. The risk associated with daily use in season relative to nonuse was 1.27 (95% Cl 0.86-1.88). The risk of breast cancer among those who reported use of the blanket through the night was 1.43 (95% Cl 0.94-2.17). However, the risk for those who reported daily use in season, continuously throughout the night for the previous 10 years was 1.10 (95% Cl 0.59-2.05). These findings do not support the hypothesis that electric blanket use is associated with an increased risk for breast cancer. Studies with improved measures of more highly exposed individuals with quantification of total electromagnetic field exposure might clarify the uncertainties regarding risk of breast cancer associated with such exposure.