Frontal lobe dysfunctions in schizophrenia--I. Eye movement impairments.

Frontal lobe dysfunctions in schizophrenia--I. Eye movement impairments.
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精神分裂症的额叶功能障碍--I.

DOI:
10.1016/0022-3956(84)90046-3
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发表时间:
1984
影响因子:
4.8
通讯作者:
Levin,S
Levin,S
中科院分区:
医学2区
文献类型:
--
作者:
Levin,S

文献摘要

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精神分裂症的眼动障碍的现象解释在本文中,第一部分的两篇论文系列,在注意力和眼动控制的神经机制的背景下。精神分裂症患者的注意力和眼球运动障碍的主要模式是由眼跳入侵引起的平稳追踪的中断,这与眼跳的去抑制是一致的。这种去抑制可能与在视觉跟踪过程中涉及扫视和平滑追踪的反馈调节的额叶眼场机制的功能障碍有关。第二种,不太具体的类型的顺利追求障碍包括扫视替代,并可能被解释为功能障碍的颞顶叶机制的任务参与。
The phenomena of eye movement impairments in schizophrenia are interpreted in this paper, Part I of a two-paper series, in the context of neural mechanisms of attention and eye movement control. The predominant pattern of attention and eye movement impairment in schizophrenia—a disruption of smooth pursuit by saccadic intrusions—is consistent with a disinhibition of saccades. This disinhibition may be related to a dysfunction of frontal eye field mechanisms involved in feedback regulation of saccades and smooth pursuit during visual tracking. A second, less specific type of smooth pursuit impairment consists of saccadic substitution, and may be interpreted in terms of a dysfunction of temporo-parietal mechanisms of task-engagement.