Mining Cytochrome b561 proteins from plant genomes.
Mining Cytochrome b561 proteins from plant genomes.
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DOI：
10.1504/ijbra.2010.032122
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发表时间：
2010
影响因子：
--
通讯作者：
Moriyama EN
中科院分区：
文献类型：
--
作者：
Opiyo SO;Moriyama EN
细胞色素b561 （Cyt-b561）蛋白在干旱条件下对植物的生长发育和防止过度光照对植物的损害具有重要意义。由于其序列相似性较低，从植物中深入挖掘Cyt-b561蛋白并不容易。目前在玉米、大豆和拟南芥基因组中分别只有1个、22个Cyt-b561基因。我们使用基于偏最小二乘法和支持向量机的无比对蛋白质分类器从植物基因组中识别出Cyt-b561。这些分类器在鉴定植物基因组中Cyt-b561相关蛋白方面优于隐马尔可夫模型和PSI-BLAST。
Cytochrome b561 (Cyt-b561) proteins are important for plant growth, development, and prevention of damage to plants from excess light under drought condition. Because of their low sequence similarity, thorough mining of Cyt-b561 proteins from plants are not easy. Currently there is only one Cyt-b561 gene in the maize, none in the soybean and twenty two in the Arabidopsis thaliana genomes, respectively. We used alignment-free protein classifiers based on partial least squares and support vector machines to identify Cyt-b561 from plant genomes. These classifiers performed better than profile hidden Markov models and PSI-BLAST in identifying Cyt-b561 related proteins from plant genomes.