Tumor Microenvironment Activable Self-Assembled DNA Hybrids for pH and Redox Dual-Responsive Chemotherapy/PDT Treatment of Hepatocellular Carcinoma.

Tumor Microenvironment Activable Self-Assembled DNA Hybrids for pH and Redox Dual-Responsive Chemotherapy/PDT Treatment of Hepatocellular Carcinoma.
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肿瘤微环境可激活自组装 DNA 杂交体用于肝细胞癌的 pH 和氧化还原双响应化疗/PDT 治疗

DOI:
10.1002/advs.201600460
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发表时间:
2017-04
期刊:
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
影响因子:
--
通讯作者:
Liu J
Liu J
中科院分区:
其他
文献类型:
--
作者:
Zhang D;Zheng A;Li J;Wu M;Cai Z;Wu L;Wei Z;Yang H;Liu X;Liu J

文献摘要

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采用智能自组装“Turn‐ON”DNA杂交体,其可以响应肿瘤微环境刺激,用于癌细胞特异性真实的实时荧光成像,肿瘤特异性协同光动力学治疗和肝细胞癌化疗。
Smart self‐assembled “Turn‐ON” DNA hybrids are employed, which could respond to tumor microenvironment stimuli for cancer cell specific real‐time fluorescence imaging, tumor‐specific synergistic photodynamic therapy and chemotherapy in hepatocellular carcinoma.