Clinical predictors of seizure recurrence after the first post-ischemic stroke seizure
Clinical predictors of seizure recurrence after the first post-ischemic stroke seizure
复制标题
DOI：
10.1186/s12883-016-0729-6
复制
发表时间：
2016-11-05
期刊：
影响因子：
2.6
通讯作者：
Lee, Hyang Woon
中科院分区：
文献类型：
--
作者：
Kim, Hyeon Jin;Park, Kee Duk;Lee, Hyang Woon
背景资料：缺血性卒中后发生卒中后癫痫（PSSi）的患者数量相当可观，特别是因为在一般人群中缺血性卒中比出血更普遍。本研究旨在确定缺血性卒中幸存者癫痫复发的预测因素，并制定一个临床评分系统，用于预测癫痫复发的风险后，第一PSSI.Methods：我们回顾了3792缺血性卒中患者梨花中风登记。共招募了124例（3.3%）发生PSSi的患者（平均随访44.4个月）。有关病因，功能障碍，癫痫发作潜伏期中风，癫痫发作类型，脑电图（EEG），和神经影像学检查结果的医疗记录进行了统计分析，以获得癫痫复发风险评分system.Results：癫痫发作复发35.4%（17/48）的早期PSSI患者（1周）的患者。晚发性PSSI患者房颤、大面积和皮质卒中病变较早发性PSSI患者多见（p < 0.05）。癫痫复发倾向于在男性、房颤或皮质卒中病变、严重功能障碍和部分性癫痫发作的早期PSSi患者中更常见。PSSi晚期组的癫痫复发在年轻患者中更常见（
Background: The number of patients suffering post-stroke seizure after ischemic stroke (PSSi) is quite considerable, especially because ischemic stroke is more prevalent than hemorrhage in the general population. This study aimed to determine the predicting factors for seizure recurrence in ischemic stroke survivors and develop a clinical scoring system for the prediction of risks for seizure recurrence after the first PSSi.Methods: We reviewed 3792 ischemic stroke patients from the Ewha Stroke Registry. A total of 124 (3.3 %) patients who experienced PSSi were recruited (mean follow-up for 44.4 months). Medical records concerning the etiology, functional disability, seizure onset latency from stroke, type of seizure, electroencephalography (EEG), and neuroimaging findings were statistically analyzed to derive a seizure recurrence risk scoring system.Results: Seizures recurred in 35.4 % (17/48) of early PSSi patients ( 1 week) patients. Atrial fibrillation, large sized, and cortical stroke lesion were more common in late onset PSSi compared to those in early onset PSSi (p < 0.05). Seizure recurrence tended to be more prevalent in early PSSi patients with male gender, atrial fibrillation or cortical stroke lesion, severe functional disability, and partial seizures. Seizure recurrence in late PSSi group was more common in patients of young age (