Birth defects surveillance: Assessing the "gold standard"

Birth defects surveillance: Assessing the "gold standard"
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DOI:
10.2105/ajph.89.8.1238
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发表时间:
1999-08-01
影响因子:
12.7
通讯作者:
Paulozzi, LJ
Paulozzi, LJ
中科院分区:
医学2区
文献类型:
--
作者:
Honein, MA;Paulozzi, LJ

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目标.本研究通过利用延迟接收数据源来评估亚特兰大大都会先天缺陷项目(MACDP)的敏感性。1997年,我们审查了1995年出生证明中以前没有被MACDP识别的潜在病例的医疗记录。捕获方法产生了总病例的估计值。我们确定了1149名缺陷婴儿,包括20名完全来自出生证明的婴儿。数据时MACDP的估计灵敏度。出生后1年时,婴儿出生证明中包含婴儿出生证明的比例为86.9%(95%CI = 80.6%,91.9%),出生后2年时增加到94.8%(95%CI = 90.3%,97.5%)。MACDP在出生后1年低估了13%的缺陷,在出生后2年低估了5%。
Objectives. This study assessed the sensitivity of tbe Metropolitan Atlanta Congenital Defects Program (MACDP) by capitalizing on the delayed receipt of a data source.Methods. In 1997, we reviewed the medical records of potential eases from the 1995 birth certificates that had not previously been identified by the MACDP. Capture meth ods produced an estimate of total cases.Results. We identified 1149 infants with defects, including 20 exclusively from birth cv:certificates. The estimated sensitivity of the MACDP when data. fram birth certificates were included tvas 86.9% (95% confidence Interval [CI] = 80.6%, 91.9%) at 1 year after birth, increasing to 94.8% (95% CI= 90.3%, 97.5%) at 2 years after birth.Conclusions. The MACDP under-estimates defects by 13% at 1 year after birth and by 5% at 2 years after birth.