Molecular Recognition of Fluorescent Probe Molecules with a Pseudopolyrotaxane Nanosheet.
Molecular Recognition of Fluorescent Probe Molecules with a Pseudopolyrotaxane Nanosheet.
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DOI：
10.1021/acsmacrolett.0c00660
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发表时间：
2021-01
影响因子：
5.8
通讯作者：
Shuntaro Uenuma;Rina Maeda;Hideaki Yokoyama;K. Ito
中科院分区：
文献类型：
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作者：
Shuntaro Uenuma;Rina Maeda;Hideaki Yokoyama;K. Ito
假聚轮烷纳米片(PPRN)是由β-环糊精(β-CD)和聚氧乙烯-b-聚氧丙烷-b-聚氧乙烷三嵌段共聚物超分子自组装而成的超薄二维(2D)材料。在本研究中，系统地研究了不同荧光探针分子在PPRN上的分子负载。PPRN对R6G吸附的1H核磁共振研究表明，R6G的甲基等小的疏水基团被PPRN吸附。不含甲基的荧光探针始终没有被吸收。这些结果表明，PPRN具有基于探针分子上官能团的主客体相互作用和PPRN表面分子尺寸的空间的分子识别吸收特性，这些空间可能是空位的β-CD和β-CD柱之间的空隙。用紫外-可见光谱研究了分子探针在PPRN上的吸附行为，其吸附行为可用朗缪尔吸附等温线很好地描述。这与建议的探针吸附在PPRN表面的模型是一致的。这项研究表明，PPRNSS可以作为有毒化合物、药物输送系统和二维传感器的吸附剂。
Pseudopolyrotaxane nanosheets (PPRNS) are ultrathin two-dimensional (2D) materials fabricated via supramolecular self-assembly of β-cyclodextrin (β-CD) and poly(ethylene oxide)-b-poly(propylene oxide)-b-poly(ethylene oxide) triblock copolymers. In this study, the molecular loading of various fluorescent probe molecules onto PPRNS was systematically investigated. 1H NMR study for R6G absorption to PPRNS indicated that the small hydrophobic groups, such as the methyl group, of R6G were absorbed by PPRNS. Consistently, the fluorescent probes without methyl groups were not absorbed. These results indicate that PPRNS has a molecular recognition absorption property based on the host-guest interaction of the functional groups on probe molecules and molecular-sized spaces of PPRNS surfaces, which may be vacant β-CDs and voids between β-CD columns. The absorbed amount of the molecular probes onto PPRNS was investigated by UV-vis spectra, and the absorption behavior could be described well by the Langmuir absorption isotherm. This is consistent with the suggested model that the probes are absorbed onto the PPRNS surfaces. This study demonstrates that PPRNSs can be applied as adsorbents for toxic compounds, drug delivery systems, and 2D sensors.