ELECTRON-MICROSCOPY AND ANTIGENIC STUDIES OF UNCHARACTERIZED VIRUSES .1. EVIDENCE SUGGESTING THE PLACEMENT OF VIRUSES IN FAMILIES ARENAVIRIDAE, PARAMYXOVIRIDAE, OR POXVIRIDAE
ELECTRON-MICROSCOPY AND ANTIGENIC STUDIES OF UNCHARACTERIZED VIRUSES .1. EVIDENCE SUGGESTING THE PLACEMENT OF VIRUSES IN FAMILIES ARENAVIRIDAE, PARAMYXOVIRIDAE, OR POXVIRIDAE
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DOI：
10.1007/bf01310934
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发表时间：
1989-01-01
影响因子：
2.7
通讯作者：
SHOPE, RE
中科院分区：
文献类型：
--
作者：
ZELLER, HG;KARABATSOS, N;SHOPE, RE
在大约35年的时间里，研究虫媒病毒生态学和流行病学的各个实验室的研究人员积累了许多病毒分离株，其中60多株没有被鉴定或归类。通过结合电子显微镜和抗原研究，我们收集了足够的信息来暂时分类60个分离株。电镜观察显示，其中20种病毒属布尼亚病毒科、20种横纹肌病毒科、14种呼肠孤病毒科、1种托加病毒科、1种副粘病毒科（来自蝙蝠的马普雷拉病毒）和1种痘病毒科（来自蚊子的Yoka病毒）。血清学研究提供了足够的证据，可以将其中一些病毒归入公认的抗原群、科和属，并为其他病毒建立新的抗原群和分类群。发现三种病毒具有与沙粒病毒科成员一致的形态和形态发生特征：人类病原体Quaranfil病毒，从鸟类和蜱中分离出来的Johnston Atoll病毒，以及从负鼠中分离出来的Araguari病毒。这是三篇系列论文中的第一篇，描述了用于这些调查的方法，并介绍了暂时属于沙粒病毒科、副粘病毒科或痘病毒科的病毒的描述。关于暂时属于布尼亚病毒科和呼肠孤病毒科的病毒的描述分别发表在第二篇和第三篇论文中。横纹肌病毒科的病毒已被单独描述。
During approximately 35 years, investigators in various laboratories studying arbovirus ecology and epidemiology accumulated many virus isolates, more than 60 of which were not characterized or placed in taxa. By a combination of electron microscopic and antigenic studies we collected information sufficient to provisionally classify 60 isolates. Electron microscopic observations suggest that 20 are members of the virus family Bunyaviridae, 20 Rhabdoviridae, 14 Reoviridae, one Togaviridae, one Paramyxoviridae (Mapuera virus, from a bat), and one Poxviridae (Yoka virus, from mosquitoes). Serologic studies provided evidence sufficient to place some of these viruses in recognized antigenic groups, within families and genera, and to establish new antigenic groups and taxa for others. Three viruses were found to have morphologic and morphogenetic characteristics consistent with those of members of the family Arenaviridae: Quaranfil virus, a human pathogen, Johnston Atoll virus, isolated from birds and ticks, and Araguari virus, isolated from an opossum. This, the first in a series of three papers, described methods used for these investigations and also presents descriptions of viruses provisionally placed in the families Arenaviridae, Paramyxoviridae, or Poxviridae. Descriptions of viruses provisionally placed in families Bunyaviridae and Reoviridae are published in the second and third papers, respectively. Viruses of the family Rhabdoviridae have been described separately.