Surface engineered hollow hydroxyapatite microspheres: Hydrothermal synthesis and growth mechanisms
Surface engineered hollow hydroxyapatite microspheres: Hydrothermal synthesis and growth mechanisms
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DOI：
10.1016/j.solidstatesciences.2020.106301
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发表时间：
2020-08-01
影响因子：
3.5
通讯作者：
Javadpour, Jafar
中科院分区：
文献类型：
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作者：
Daryan, Sahar Hashemi;Khavandi, Alireza;Javadpour, Jafar
采用无模板剂水热法制备了有序的中空羟基磷灰石微球。柠檬酸盐在本研究中用作螯合剂或形态调节剂。在调节剂存在下，二维三斜磷钙石相转变为三维中空羟基磷灰石微球，平均直径为4 μ m。扫描电子显微镜（SEM）和透射电子显微镜（TEM）的研究表明，柠檬酸/钙（Cit/Ca）的比例在调节颗粒形态的重要性。结果表明，通过调节表面修饰剂的浓度，可以将微球的表面形貌从纳米片结构改造为纳米棒结构。X射线衍射（XRD）和傅里叶变换红外（FTIR）光谱证实了合成粉末的结晶度和纯度。Brunauer-Emmett-Teller（BET）表明，随着表面上纳米片羟基磷灰石微球（HAMNS）到纳米棒羟基磷灰石微球（HAMNR）的变化，比表面积增加。热力学和动力学理论，提出了解释所观察到的表面形态和晶体生长的变化。
Well-organized hollow hierarchical hydroxyapatite microspheres were prepared hydrothermally via a template free process. Citrate was used as chelating or morphology regulating agent in this study. In the presence of regulating agent two-dimensional monetite phase evolved into three-dimensional hollow hydroxyapatite mi-crospheres with an average diameter of 4 mu m. Scanning electron microscopy (SEM) and transmission electron microscopy (TEM) studies revealed the importance of Citrate/Calcium (Cit/Ca) ratio in regulating the particle morphology. The results indicate that the surface morphology of microspheres can be engineered from nano sheets to nanorods by regulating agent concentration. X-ray diffraction (XRD) and Fourier transform infrared (FTIR) spectroscopy confirmed crystallinity and purity in the synthesized powders. Brunauer-Emmett-Teller (BET) indicated an increase in the specific surface area with the change from hydroxyapatite microspheres with nanosheets (HAMNS) to hydroxyapatite microspheres with nanorods (HAMNR) on the surface. Thermodynamic and kinetic theories are proposed to account for the observed changes in the surface morphology and crystal growth.