The innate resistance of Kenana cattle to tropical theileriosis (Theileria annulata infection) in the Sudan
The innate resistance of Kenana cattle to tropical theileriosis (Theileria annulata infection) in the Sudan
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DOI：
10.1111/j.1749-6632.2002.tb04370.x
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发表时间：
2002-01-01
期刊：
影响因子：
--
通讯作者：
Latif, AA
中科院分区：
文献类型：
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作者：
Bakheit, MA;Latif, AA
开展了一项研究，以评估苏丹本土品种凯纳牛对热带泰勒虫病、环形泰勒氏菌感染的先天抵抗力。从无热带泰勒虫病和媒介硬蜱的地区获得9头易感凯纳纳牛犊，间接荧光抗体试验均为环带绦虫抗体阴性。接种环纹夜蛾1.0mL子孢子稳定剂感染。三头弗里斯牛犊也被感染，并作为敏感对照。凯纳牛的裂殖体寄生率(Macroschont Index，MSI)比弗里斯小牛降低了70%。在凯纳纳犊牛中，旋毛虫寄生虫血症的百分比也明显较低。弗里西亚小牛的白细胞减少率明显更高(P<；0.05)。这些差异归因于对照牛的裂殖体增殖率较高。78%(7/9)的凯纳牛自发康复，只有22%的牛需要治疗，而弗里西亚对照组的死亡率为100%。这些差异归因于对照牛的裂殖体增殖率很高，另一方面，Kenana牛有能力限制MSI，导致在疾病急性期对淋巴组织的损害较轻。
A study was carried out to assess the innate resistance of the indigenous Kenana breed of cattle in the Sudan to tropical theileriosis, Theileria annulata infection of cattle. Nine susceptible Kenana calves were obtained from an area free from tropical theileriosis and the vector tick Hyalomma anatolicum anatolicum and were found negative to T annulata antibodies in the indirect fluorescent antibody test. They were infected by inoculation of 1.0 mL T annulata sporozoite stabilate. Three Friesian calves were also infected and served as susceptible controls. The percent of schizont parasitosis (Macroschizont Index, MSI) in the Kenana cattle was reduced by 70% compared to the Friesian calves. The percent of piroplasm parasitemia was also significantly lower in the Kenana calves. The rate of white blood cell reduction was significantly greater in the Friesian calves (P < 0.05). These differences were attributed to the high rate of schizont multiplication in the control cattle. Seventy-eight percent (7/9) of the Kenana cattle recovered spontaneously, and only 22% required treatment compared to 100% mortality in the Friesian controls. These differences were attributed to the high rate of schizont multiplication in the control cattle and, on the other hand, ability of the Kenana cattle to limit the MSI, resulting in less severe damage to the lymphoid tissue during the acute phase of the disease.