Bacterial translocation or lymphatic drainage of toxic products from the gut: What is important in human beings?
Bacterial translocation or lymphatic drainage of toxic products from the gut: What is important in human beings?
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DOI：
10.1067/msy.2002.116408
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发表时间：
2002-03-01
期刊：
影响因子：
3.8
通讯作者：
Deitch, EA
中科院分区：
文献类型：
--
作者：
Deitch, EA
结论MODS的肠源性假说在过去的20年里经历了一系列的概念变化。最初提出，肠道来源的细菌、内毒素或两者移位到血流和全身组织中起作用以触发脓毒症状态，从而促进MODS的发展。虽然细菌移位的概念在概念上是有吸引力的，但随着更多数据的积累，很明显，细菌和内毒素移位的想法是可行的。
ConclusionThe gut origin hypothesis of MODS has undergone a series of conceptual changes over the past 20 years. It was originally proposed that intestinally derived bacteria, endotoxin, or both translocating to the blood stream and systemic tissues acted to trigger a septic state and thereby promoted the development of MODS. Although the concept of bacterial translocation was conceptually attractive, as more data accumulated, it became clear that the idea of translocating bacteria and endotoxin being