Left-right cortical asymmetries of regional cerebral blood flow during listening to words.
Left-right cortical asymmetries of regional cerebral blood flow during listening to words.
复制标题
听单词时局部脑血流的左右皮质不对称。
作者：
Y. Nishizawa;T. S. Olsen;B. Larsen;N. Lassen
1.在休息和听简单单词时测量局部脑血流量（rCBF）。使用氙133颈动脉内技术，从七个右半球和七个左半球的254个区域获得结果。测量是在颈动脉血管造影后立即进行的，以排除占位性病变。所有受试者的血管造影均正常。所有人都是右利手。 2. 听任务期间，左半球和右半球的平均半球血流量比静息测量增加了 10%。这种增加的部分原因是整个半球的激活。局灶性 rCBF 增加局限于颞区上部、前额叶区、额眼区和眶额区。发现明显的不对称性，特别是在颞上区，左侧显示出更广泛和强烈的增加，平均为 29%，而右侧为 18%。言语刺激期间的这种左侧优势应该与 Roland 等人报告的非言语声音辨别期间 rCBF 的右侧优势进行比较。 (25, 26)，他们使用了与本研究完全相同的技术。
1. Regional cerebral blood flow (rCBF) was measured during rest and during listening to simple words. The xenon-133 intracarotid technique was used and results were obtained from 254 regions of seven right hemispheres and seven left hemispheres. The measurements were performed just after carotid angiography, carried out to exclude space occupying lesions. In all subjects the angiogram was normal. All were right handed. 2. Mean hemispheric blood flow of both left and right hemispheres increased 10% from the resting measurement during the listening task. This increase was due in part to activation of the entire hemisphere. The focal rCBF increases were localized to the superior part of the temporal regions, the prefrontal regions, the frontal eye fields, and the orbitofrontal regions. Significant asymmetries were found in particular in the superior temporal region with the left side showing a more widespread and intense increase, averaging 29% as compared to 18% on the right side. This left-sided dominance during verbal stimulation should be compared to the right-sided dominance of rCBF during nonverbal sound discrimination reported by Roland et al. (25, 26), who used precisely the same technique as in the present study.