Laboratory evaluation of a double lumen catheter for venovenous neonatal ECMO.
Laboratory evaluation of a double lumen catheter for venovenous neonatal ECMO.
复制标题
用于新生儿静脉 ECMO 的双腔导管的实验室评估。
DOI：
10.1097/00002480-198907000-00156
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发表时间：
1989
期刊：
影响因子：
--
通讯作者：
R. Bartlett
中科院分区：
文献类型：
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作者：
T. Otsu;S. Merz;K. Hultquist;R. Attorri;H. Anderson,;D. Scheffler;A. Ahmad;R. Bartlett
作者设计并测试了用于新生儿静脉-静脉（VV）体外膜肺氧合（ECMO）的14 F外径薄壁双腔导管（DLC）。使用水和染料溶液的体外试验显示，在100 cm虹吸管处引流腔的容量为1，096 ml/min，在500 ml/min流速下灌注腔的压降为300 mmHg。根据模拟心输出量，500 ml/min流速下的再循环范围为5 - 29%。5只犬在12小时400 ml/min流量VV旁路期间的最高血清血红蛋白为49 mg/dl。在400 ml/min流速下，4只犬的典型氧转运为25 cc/min。该导管非常适合新生儿临床VV ECMO。
The authors designed and tested a 14F outside diameter thin-walled double lumen catheter (DLC) for neonatal venovenous (VV) extracorporeal membrane oxygenation (ECMO). In vitro tests with water and dye solution showed capacity of the drainage lumen was 1,096 ml/min at 100 cm siphon, and pressure drop across the perfusion lumen was 300 mmHg at 500 ml/min flow. Recirculation at 500 ml/min flow ranged from 5 to 29%, depending upon simulated cardiac output. The highest serum hemoglobin during 12 hour 400 ml/min flow VV bypass in five dogs was 49 mg/dl. Typical oxygen transport in four dogs was 25 cc/min at 400 ml/min flow. This catheter is well suited for clinical VV ECMO in neonates.