A hierarchical neuronal network for planning behavior
A hierarchical neuronal network for planning behavior
复制标题
DOI：
10.1073/pnas.94.24.13293
复制
发表时间：
1997-11-25
影响因子：
11.1
通讯作者：
Changeux, JP
中科院分区：
文献类型：
--
作者：
Dehaene, S;Changeux, JP
规划目标导向的行为序列是人类大脑的高级功能，它依赖于前额皮质区域的完整性。在伦敦塔测试中，必须移动在木桩上滑动的珠子以匹配指定的目标配置，前额叶皮层受损的患者在计划目标导向的动作序列方面表现出缺陷。我们提出了一个序列规划的神经网络模型，该模型通过了这一测试，并且当受损时，以模仿前额叶患者行为的方式失败。我们的模型包括一个向下的计划系统，该系统具有分层组织的计划，操作和手势级别，以及一个向上的评估系统，该系统分析问题并计算内部奖励信号，以索引计划的正确/错误状态。连接评估和规划系统的多个并行路径修改计划并使其适应当前的问题。该模型说明了专门的层次组织的神经元集合如何共同模拟人类大脑的中央执行或监督功能。
Planning a goal-directed sequence of behavior is a higher function of the human brain that relies on the integrity of prefrontal cortical areas. In the Tower of London test, a puzzle in which beads sliding on pegs must be moved to match a designated goal configuration, patients with lesioned prefrontal cortex show deficits in planning a goal-directed sequence of moves. We propose a neuronal network model of sequence planning that passes this test and, when lesioned, fails in a way that mimics prefrontal patients' behavior. Our model comprises a descending planning system with hierarchically organized plan, operation, and gesture levels, and an ascending evaluative system that analyzes the problem and computes internal reward signals that index the correct/erroneous status of the plan. Multiple parallel pathways connecting the evaluative and planning systems amend the plan and adapt it to the current problem. The model illustrates how specialized hierarchically organized neuronal assemblies may collectively emulate central executive or supervisory functions of the human brain.