Otitis media with effusion in children with in Down syndrome
Otitis media with effusion in children with in Down syndrome
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DOI：
10.1016/j.ijporl.2013.05.027
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发表时间：
2013-08-01
影响因子：
1.5
通讯作者：
Kvaerner, Kari Jorunn
中科院分区：
文献类型：
--
作者：
Austeng, Marit Erna;Akre, Harriet;Kvaerner, Kari Jorunn
目的：目的：探讨唐氏综合征（DS）患儿渗出性中耳炎（OME）的患病率及其与8岁时听力损失的关系。研究设计：对2002年出生于挪威的所有DS患儿进行一项基于全国人口的临床研究。OME患儿的听力水平显著低于无OME患儿，其平均纯音平均值（PTA）为33.4 dB HL，而无OME患儿的平均PTA为21.7 dB HL（p < 0.0001）。经验证的听力损失超过25 dB HL的听力较好的耳朵被发现在12的20 OME，相比之下，5的31 OME。结论：本研究的结果揭示了增加的风险OME在8岁的儿童DS作为当前中耳炎被发现在三个。由于OME导致的DS儿童在8岁时听力下降，强烈强调了最佳治疗和随访的必要性，以优化听力康复。研究设计以人口为基础，注重年龄段窄和答复率高，这些都进一步支持了研究结果。(C)2013爱思唯尔爱尔兰有限公司版权所有。
Objective: To determine the prevalence of otitis media with effusion (OME) in children with Down syndrome (DS), and the associated to hearing loss at the age of 8 years.Study design: A national population based clinical study of all children with DS born in Norway in 2002.Results: OME was found in 20 out of 52 (38%) children. Those with OME had a significant lower hearing level with a Mean pure tone average (PTA) of 33.4 dB HL compared to children with no OME whose mean PTA was 21.7 dB HL (p < 0.0001). Verified hearing loss above 25 dB HL in the better hearing ear was found in 12 out of the 20 with OME, compared to 5 out 31 without OME.Conclusion: The findings of this present study uncover the increased risk of OME in eight year old children with DS as current otitis media was found in one of three. This reduced hearing ability in children with DS due to OME at age of 8 strongly emphasizes the need for optimal treatment and follow up to optimize hearing rehabilitation. The findings are further supported by the population based study design, the focus on the narrow age band and the high response rate. (C) 2013 Elsevier Ireland Ltd. All rights reserved.